2024
BMI and breast cancer risk around age at menopause
Von Holle A, Adami H, Baglietto L, Berrington de Gonzalez A, Bertrand K, Blot W, Chen Y, DeHart J, Dossus L, Eliassen A, Fournier A, Garcia-Closas M, Giles G, Guevara M, Hankinson S, Heath A, Jones M, Joshu C, Kaaks R, Kirsh V, Kitahara C, Koh W, Linet M, Park H, Masala G, Mellemkjaer L, Milne R, O'Brien K, Palmer J, Riboli E, Rohan T, Shrubsole M, Sund M, Tamimi R, Tin Tin S, Visvanathan K, Vermeulen R, Weiderpass E, Willett W, Yuan J, Zeleniuch-Jacquotte A, Nichols H, Sandler D, Swerdlow A, Schoemaker M, Weinberg C. BMI and breast cancer risk around age at menopause. Cancer Epidemiology 2024, 89: 102545. PMID: 38377945, PMCID: PMC10942753, DOI: 10.1016/j.canep.2024.102545.Peer-Reviewed Original ResearchConceptsBreast cancer riskCancer riskHazard ratioBreast cancer hazard ratioCancer hazard ratioFive-unit incrementNatural menopauseBreast cancer etiologyHigher body mass indexLoss to follow-upAssociated with decreased riskBreast cancer diagnosisMenopausal status groupsBody mass indexYears age rangeMenopausal hormone therapyPrimary time scalePerson-timeCancer etiologyLoss of ovarian functionCancer diagnosisMass indexBMIPositive associationStatus groups
2023
International Pooled Analysis of Leisure-Time Physical Activity and Premenopausal Breast Cancer in Women From 19 Cohorts
Timmins I, Jones M, O'Brien K, Adami H, Aune D, Baglietto L, Bertrand K, Brantley K, Chen Y, DeHart J, Clendenen T, Dossus L, Eliassen A, Fletcher O, Fournier A, Håkansson N, Hankinson S, Houlston R, Joshu C, Kirsh V, Kitahara C, Koh W, Linet M, Park H, Lynch B, May A, Mellemkjær L, Milne R, Palmer J, Ricceri F, Rohan T, Ruddy K, Sánchez M, Shu X, Smith-Byrne K, Steindorf K, Sund M, Vachon C, Vatten L, Visvanathan K, Weiderpass E, Willett W, Wolk A, Yuan J, Zheng W, Nichols H, Sandler D, Swerdlow A, Schoemaker M. International Pooled Analysis of Leisure-Time Physical Activity and Premenopausal Breast Cancer in Women From 19 Cohorts. Journal Of Clinical Oncology 2023, 42: 927-939. PMID: 38079601, PMCID: PMC10927335, DOI: 10.1200/jco.23.01101.Peer-Reviewed Original ResearchLeisure-time physical activityLevels of leisure-time physical activityBreast cancer riskPremenopausal breast cancerBreast cancer risk factorsPhysical activityCancer risk factorsCancer riskHazard ratioHigher levels of leisure-time physical activityAssociations of leisure-time physical activityLow levels of leisure-time physical activitySelf-reported leisure-time physical activityIncident cases of breast cancerAssociation of physical activityPostmenopausal breast cancer riskPremenopausal breast cancer riskBreast cancerPooled analysis of cohort studiesPooled individual-level dataCohort studyAnalysis of cohort studiesBreast cancer incidenceCases of breast cancerEstimate hazard ratiosPrediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study
Hughes D, Schomburg L, Jenab M, Biessy C, Méplan C, Moskal A, Sun Q, Demircan K, Fedirko V, Weiderpass E, Mukhtar M, Olsen A, Tjønneland A, Overvad K, Schulze M, Nøst T, Skeie G, Olsen K, Ricceri F, Grioni S, Palli D, Masala G, Tumino R, Pasanisi F, Amiano P, Colorado Yohar S, Agudo A, Sánchez M, Ardanaz E, Sund M, Andersson A, Perez-Cornago A, Travis R, Heath A, Dossus L. Prediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study. Free Radical Biology And Medicine 2023, 209: 381-393. PMID: 37923090, DOI: 10.1016/j.freeradbiomed.2023.10.401.Peer-Reviewed Original ResearchConceptsAssociated with BC riskBC riskCase-control pairsOdds ratioMultivariable-adjusted logistic regression modelsBreast cancer riskInfluence BC riskCancer and NutritionConfidence intervalsEuropean Prospective InvestigationHigher risk of BCPremenopausal BC riskRisk of BCPrevent breast cancerAssociated with lower riskEuropean cohort studiesBreast cancerGenetic variant associationsLogistic regression modelsGlutathione peroxidase 3Multiple testing correctionStatistically significant associationPremenopausal BCCancer riskVariant associations