2023
High prevalence of low high‐density lipoprotein cholesterol and insulin resistance among children and adolescents living with HIV in Uganda: harbinger for metabolic syndrome?
Kisitu G, Shabanova V, Naiga F, Nakagwa M, Kekitiinwa A, Elyanu P, Paintsil E. High prevalence of low high‐density lipoprotein cholesterol and insulin resistance among children and adolescents living with HIV in Uganda: harbinger for metabolic syndrome? HIV Medicine 2023, 25: 262-275. PMID: 37879630, DOI: 10.1111/hiv.13570.Peer-Reviewed Original ResearchInternational Diabetes FederationLow high-density lipoprotein cholesterolHigh-density lipoprotein cholesterolPrevalence of MetSInsulin resistanceLipoprotein cholesterolMetabolic syndromeAdult Treatment Panel criteriaHomeostatic model assessment indexCross-sectional pilot studyFrequency of MetSModel assessment indexHOMA-IR indexOlder age groupsAge-dependent prevalenceAssociated health problemsATPIII criteriaCentral obesityBlood pressureDiabetes FederationPrimary outcomeClinical centersLifetime riskPanel criteriaHigh prevalence
2018
2247. Antiretrovirals Perturb Cholesterol Biosynthesis in PBMCs of HIV-Infected Individuals
Sopeyin A, Li M, Paintsil E. 2247. Antiretrovirals Perturb Cholesterol Biosynthesis in PBMCs of HIV-Infected Individuals. Open Forum Infectious Diseases 2018, 5: s664-s665. PMCID: PMC6252475, DOI: 10.1093/ofid/ofy210.1900.Peer-Reviewed Original ResearchAntiretroviral therapyMetabolic syndromeTenofovir/emtricitabine/efavirenzEffect of ARTHispanic whitesCholesterol biosynthesisZidovudine/lamivudineCase-control studyLow-density lipoprotein receptorSterol regulatory element-binding protein 2Non-Hispanic whitesDensity lipoprotein receptorRace/ethnicityAge of participantsART regimenWilcoxon rank testMetabolic derangementsViral loadHealthy controlsCardiovascular diseaseCopies/High prevalenceTherapeutic benefitSide effectsLipoprotein receptor