Inhibition of exocytosis or endocytosis blocks activity‐dependent redistribution of synapsin
Orenbuch A, Shulman Y, Lipstein N, Bechar A, Lavy Y, Brumer E, Vasileva M, Kahn J, Barki‐Harrington L, Kuner T, Gitler D. Inhibition of exocytosis or endocytosis blocks activity‐dependent redistribution of synapsin. Journal Of Neurochemistry 2011, 120: 248-258. PMID: 22066784, DOI: 10.1111/j.1471-4159.2011.07579.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornCells, CulturedChelating AgentsEgtazic AcidEndocytosisEnzyme InhibitorsExcitatory Amino Acid AntagonistsExocytosisFemaleGreen Fluorescent ProteinsHippocampusHydrazonesIntracellular Signaling Peptides and ProteinsMaleMembrane PotentialsMiceMice, Inbred C57BLMice, KnockoutNerve Tissue ProteinsNeuronsNeurotoxinsPatch-Clamp TechniquesPhosphorylationStatistics, NonparametricSynapsesSynapsinsSynaptic VesiclesTetanus ToxinTransfectionConceptsSynaptic vesicle cycleActivity-dependent redistributionVesicle cycleDynamin dominant-negative mutantDominant negative mutantPerturbation of endocytosisReserve pool vesiclesEfficient phosphorylationCultured mouse hippocampal neuronsPlasma membraneMouse hippocampal neuronsInhibition of exocytosisPool vesiclesEndocytosisSynaptic vesiclesPre-synaptic terminalsExocytosisSynapsinVesiclesReserve poolRelease of neurotransmittersPhosphorylationRelease sitesReserve vesiclesReleasable pool