2018
Somatosensory Neurons Enter a State of Altered Excitability during Hibernation
Hoffstaetter LJ, Mastrotto M, Merriman DK, Dib-Hajj SD, Waxman SG, Bagriantsev SN, Gracheva EO. Somatosensory Neurons Enter a State of Altered Excitability during Hibernation. Current Biology 2018, 28: 2998-3004.e3. PMID: 30174191, PMCID: PMC6173314, DOI: 10.1016/j.cub.2018.07.020.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsArousalBody TemperatureCold TemperatureHibernationSciuridaeSensory Receptor CellsConceptsSomatosensory neuronsAction potentialsPeripheral somatosensory neuronsVoltage-gated sodium channelsTherapeutic hypothermiaAltered excitabilityFunctional deficitsCase of neuronsSensory functionFiring patternsNeuronsCold exposureInput resistanceSodium channelsRapid restorationBody temperatureHypometabolismHypothermiaDevelopment of strategiesSensory informationProlonged periodAdaptive responseArousalCNSExcitability
2010
Molecular basis of infrared detection by snakes
Gracheva EO, Ingolia NT, Kelly YM, Cordero-Morales JF, Hollopeter G, Chesler AT, Sánchez EE, Perez JC, Weissman JS, Julius D. Molecular basis of infrared detection by snakes. Nature 2010, 464: 1006-1011. PMID: 20228791, PMCID: PMC2855400, DOI: 10.1038/nature08943.Peer-Reviewed Original ResearchConceptsTranscriptional profiling approachVertebrate nervous systemTransient receptor potential channelsPit organsMolecular basisEvolutionary tuningUnique sensory systemPhotochemical transductionIon channelsProfiling approachSnakesPotential channelsNerve fibersPrimary transducerSensory systemsPredatorsOrgansPreySensory nerve fibersTransductionTRPA1 channelsNervous systemTransducesThermosensorsInfrared receptors