Support for the hypothesis that successful immunotherapy of various cancers can be achieved by inhibiting a progesterone associated immunomodulatory protein
Check J, Dix E, Sansoucie L. Support for the hypothesis that successful immunotherapy of various cancers can be achieved by inhibiting a progesterone associated immunomodulatory protein. Medical Hypotheses 2008, 72: 87-90. PMID: 18842348, DOI: 10.1016/j.mehy.2008.05.042.Peer-Reviewed Original ResearchConceptsPIBF proteinCancer cellsProgesterone secretionLeukemia cell linesProgesterone receptor antagonist mifepristoneImmunomodulatory proteinsQuality of lifeCell linesAnecdotal improvementMifepristone therapySuccessful immunotherapyAntagonist mifepristoneNormal pregnancyNormal body functionType therapyProgesterone receptorImmune surveillanceHuman leukemia cell linesMetastatic human cancersSpontaneous cancersProgesteroneCancerBody functionsTherapyProtein expression