2001
Regulation of Cutaneous Malignancy by γδ T Cells
Girardi M, Oppenheim D, Steele C, Lewis J, Glusac E, Filler R, Hobby P, Sutton B, Tigelaar R, Hayday A. Regulation of Cutaneous Malignancy by γδ T Cells. Science 2001, 294: 605-609. PMID: 11567106, DOI: 10.1126/science.1063916.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsCarcinogensCell LineCytotoxicity, ImmunologicDimerizationEpidermisEpithelial CellsHistocompatibility Antigens Class IHumansImmunologic SurveillanceLigandsMembrane ProteinsMiceMice, Inbred C57BLMinor Histocompatibility AntigensMolecular Sequence DataNK Cell Lectin-Like Receptor Subfamily KProtein ConformationProtein FoldingReceptors, Antigen, T-Cell, alpha-betaReceptors, Antigen, T-Cell, gamma-deltaReceptors, ImmunologicReceptors, Natural Killer CellRecombinant Fusion ProteinsReverse Transcriptase Polymerase Chain ReactionSkin NeoplasmsT-Lymphocyte SubsetsConceptsT cellsGammadelta cellsLocal T cellsNatural killer cellsΓδ T cellsGammadelta T cellsCytolytic T cellsSkin carcinoma cellsNKG2D engagementMultiple regimensKiller cellsCutaneous malignanciesCutaneous carcinogenesisEpithelial malignanciesRAE-1Human MICAMalignancyCarcinoma cellsSkin cellsCellsNKG2DRegimensMiceEpitheliumCarcinogenesisInduction of human tumor‐loaded dendritic cells
Berger C, Xu A, Hanlon D, Lee C, Schechner J, Glusac E, Christensen I, Snyder E, Holloway V, Tigelaar R, Edelson R. Induction of human tumor‐loaded dendritic cells. International Journal Of Cancer 2001, 91: 438-447. PMID: 11251964, DOI: 10.1002/1097-0215(200002)9999:9999<::aid-ijc1073>3.0.co;2-r.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, CDApoptosisCD36 AntigensCell DifferentiationCell DivisionCell SurvivalCells, CulturedCytokinesCytoplasmDendritic CellsDose-Response Relationship, DrugFlow CytometryHumansImmunoglobulinsImmunohistochemistryImmunophenotypingImmunotherapyLeukapheresisLeukocytesLymphocytesMajor Histocompatibility ComplexMembrane GlycoproteinsMonocytesPhagocytosisPhenotypeTime FactorsT-LymphocytesConceptsExtracorporeal photopheresisDistinctive antigensTumor-loaded dendritic cellsStandard extracorporeal photopheresisMHC class II moleculesImproved cancer immunotherapyDendritic cell differentiationAnti-cancer vaccinesMalignant T cellsClass II moleculesTransition of monocytesDC vaccinesMalignant cell apoptosisDendritic cellsImmature DCsCancer immunotherapyCD83 expressionT cellsExogenous cytokinesSignificant proliferationCell apoptosisVaccineMembrane CD36Cell differentiationCells
1998
Mycosis Fungoides Palmaris et Plantaris or Acral Pagetoid Reticulosis?
McNiff J, Schechner J, Crotty P, Glusac E. Mycosis Fungoides Palmaris et Plantaris or Acral Pagetoid Reticulosis? American Journal Of Dermatopathology 1998, 20: 271-275. PMID: 9650701, DOI: 10.1097/00000372-199806000-00009.Peer-Reviewed Original ResearchConceptsMycosis fungoides palmaris et plantarisWoringer-Kolopp diseasePalmaris et plantarisPagetoid reticulosisEpidermotropic atypical lymphocytesPolymerase chain reaction studiesT-cell receptor betaT-cell clonalityClonal gene rearrangementsEpidermotropic lymphocytesRecurrent plaquesAtypical lymphocytesCutaneous plaquesSuppressor/Dermal infiltrateMycosis fungoidesSystemic diseaseAcral sitesT cellsBiologic potentialHistologic resemblanceIntraepidermal lymphocytesReceptor betaDiseasePlantaris
1994
T lymphocytes bearing the γ/δ T‐cell receptor in cutaneous lesions of dermatitis herpetiformis
Kell D, Glusac E, Smoller B. T lymphocytes bearing the γ/δ T‐cell receptor in cutaneous lesions of dermatitis herpetiformis. Journal Of Cutaneous Pathology 1994, 21: 413-418. PMID: 7868753, DOI: 10.1111/j.1600-0560.1994.tb00282.x.Peer-Reviewed Original ResearchConceptsGamma/delta T cell receptorT cell receptorDelta T-cell receptorDermatitis herpetiformisCutaneous lesionsT lymphocytesAlpha/beta T cell receptorGamma/delta T cell subsetGamma/delta T cellsBeta T cell receptorCell receptorPerilesional skin biopsiesSubset of lymphocytesT cell subsetsPositive T lymphocytesDelta T cellsStandard immunoperoxidase techniqueGamma/delta receptorIL-2 receptorGastrointestinal biopsiesInflammatory dermatosesCell subsetsInflammatory conditionsSkin biopsiesT cells