2014
Maternal Buffering of Human Amygdala-Prefrontal Circuitry During Childhood but Not During Adolescence
Gee DG, Gabard-Durnam L, Telzer EH, Humphreys KL, Goff B, Shapiro M, Flannery J, Lumian DS, Fareri DS, Caldera C, Tottenham N. Maternal Buffering of Human Amygdala-Prefrontal Circuitry During Childhood but Not During Adolescence. Psychological Science 2014, 25: 2067-2078. PMID: 25280904, PMCID: PMC4377225, DOI: 10.1177/0956797614550878.Peer-Reviewed Original ResearchConceptsAmygdala-prefrontal circuitryMaternal bufferingMaternal stimuliAmygdala-prefrontal connectivityMature connectivityAmygdala reactivityPotential mechanismsMaternal modulationChildhoodMother-child relationshipNeural mechanismsSensitive periodChildrenCaregiversMaternal influenceRegulatory influenceAdolescenceStimuliBehavioral regulationNeurocircuitryCircuitry
2013
A Developmental Shift from Positive to Negative Connectivity in Human Amygdala–Prefrontal Circuitry
Gee DG, Humphreys KL, Flannery J, Goff B, Telzer EH, Shapiro M, Hare TA, Bookheimer SY, Tottenham N. A Developmental Shift from Positive to Negative Connectivity in Human Amygdala–Prefrontal Circuitry. Journal Of Neuroscience 2013, 33: 4584-4593. PMID: 23467374, PMCID: PMC3670947, DOI: 10.1523/jneurosci.3446-12.2013.Peer-Reviewed Original ResearchConceptsAmygdala-prefrontal circuitryFunctional connectivityNegative connectivityAmygdala reactivityRecent human imagingParticipants 10 yearsTask-based functional magnetic resonance imagingNegative functional connectivityFunctional magnetic resonance imagingMagnetic resonance imagingAmygdala-prefrontal connectivityAmygdala-cortical connectivityAnxiety-related disordersFrontoamygdala circuitryAnimal studiesReciprocal connectionsResonance imagingTracing studyPositive connectivityAdolescent periodEarly childhoodNeurobiological basisEmotional behaviorPresent studyDevelopmental changes