Featured Publications
Neural effects of controllability as a key dimension of stress exposure
Cohodes EM, Odriozola P, Mandell JD, Caballero C, McCauley S, Zacharek SJ, Hodges HR, Haberman JT, Smith M, Thomas J, Meisner OC, Ellis CT, Hartley CA, Gee DG. Neural effects of controllability as a key dimension of stress exposure. Development And Psychopathology 2022, 35: 218-227. PMID: 35034670, DOI: 10.1017/s0954579421001498.Peer-Reviewed Original ResearchConceptsDorsal anterior insulaRight dorsal anterior insulaUncontrollable stress conditionUncontrollable stressStress exposureSex-matched participantsStressor controllabilityInitial exposureFunctional magnetic resonance imaging (fMRI) acquisitionSubsequent stress exposureNeural effectsAnterior insulaYoung adultsSubsequent stressorsPatterns of activityCross-species evidenceNeural correlatesSubsequent exposureExposureNeural underpinningsPresent studyParticipantsMagnetic resonance imaging (MRI) acquisitionAdaptive responseFMRI analysis
2019
Novel insights from actigraphy: Anxiety is associated with sleep quantity but not quality during childhood
Cohodes EM, Abusch A, Odriozola P, Gee DG. Novel insights from actigraphy: Anxiety is associated with sleep quantity but not quality during childhood. Clinical Child Psychology And Psychiatry 2019, 25: 189-199. PMID: 30696260, PMCID: PMC6667310, DOI: 10.1177/1359104518822685.Peer-Reviewed Original ResearchConceptsSleep quantitySleep-related interventionsSleep functionPredictors of anxietyPediatric clinical samplesAge-related changesHigh anxietyAnxietyPediatric samplesPrevious researchSleep dysfunctionClinical samplesChildhoodFunction changesAdolescenceAdolescentsActigraphyPresent studyYouthQuantitative measuresCorrelatesAssociationSleepChildrenIntervention
2013
A Developmental Shift from Positive to Negative Connectivity in Human Amygdala–Prefrontal Circuitry
Gee DG, Humphreys KL, Flannery J, Goff B, Telzer EH, Shapiro M, Hare TA, Bookheimer SY, Tottenham N. A Developmental Shift from Positive to Negative Connectivity in Human Amygdala–Prefrontal Circuitry. Journal Of Neuroscience 2013, 33: 4584-4593. PMID: 23467374, PMCID: PMC3670947, DOI: 10.1523/jneurosci.3446-12.2013.Peer-Reviewed Original ResearchConceptsAmygdala-prefrontal circuitryFunctional connectivityNegative connectivityAmygdala reactivityRecent human imagingParticipants 10 yearsTask-based functional magnetic resonance imagingNegative functional connectivityFunctional magnetic resonance imagingMagnetic resonance imagingAmygdala-prefrontal connectivityAmygdala-cortical connectivityAnxiety-related disordersFrontoamygdala circuitryAnimal studiesReciprocal connectionsResonance imagingTracing studyPositive connectivityAdolescent periodEarly childhoodNeurobiological basisEmotional behaviorPresent studyDevelopmental changes
2010
Low frequency fluctuations reveal integrated and segregated processing among the cerebral hemispheres
Gee DG, Biswal BB, Kelly C, Stark DE, Margulies DS, Shehzad Z, Uddin LQ, Klein DF, Banich MT, Castellanos FX, Milham MP. Low frequency fluctuations reveal integrated and segregated processing among the cerebral hemispheres. NeuroImage 2010, 54: 517-527. PMID: 20570737, PMCID: PMC3134281, DOI: 10.1016/j.neuroimage.2010.05.073.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityFunctional magnetic resonance imagingFunctional connectivityResting-state functional magnetic resonance imagingInterhemispheric interactionsResting-state fMRI scansSpontaneous low-frequency fluctuationsLow-frequency fluctuationsInterhemispheric processingMagnetic resonance imagingRSFC strengthCerebral hemispheresHomotopic regionsIntrahemispheric processingResonance imagingNegative connectivityEntire cerebrumConnectivity strengthFMRI scansHealthy participantsBOLD signalSegregated processingPresent studyOpposite hemisphereHemisphere