2020
Learning About Safety: Conditioned Inhibition as a Novel Approach to Fear Reduction Targeting the Developing Brain
Odriozola P, Gee DG. Learning About Safety: Conditioned Inhibition as a Novel Approach to Fear Reduction Targeting the Developing Brain. American Journal Of Psychiatry 2020, 178: 136-155. PMID: 33167673, PMCID: PMC7951569, DOI: 10.1176/appi.ajp.2020.20020232.Peer-Reviewed Original ResearchConceptsSafety signal learningExtinction learningSignal learningAnxiety disordersAnxious youthSafety cuesDorsal anterior cingulate cortexInhibition of fearFronto-amygdala circuitryCross-species evidenceAnterior cingulate cortexFear responsesAnxiety-like behaviorFrontolimbic circuitryCingulate cortexNeural circuitryCore featuresPrelimbic cortexBasic neuroscienceTranslational frameworkCuesYouthFearLearningAnimal models
2018
Implications of the Research Domain Criteria project for childhood anxiety and its disorders
Lebowitz ER, Gee DG, Pine DS, Silverman WK. Implications of the Research Domain Criteria project for childhood anxiety and its disorders. Clinical Psychology Review 2018, 64: 99-109. PMID: 29526524, PMCID: PMC6668617, DOI: 10.1016/j.cpr.2018.01.005.Peer-Reviewed Original ResearchConceptsChildhood anxiety disordersChildhood anxietyResearch Domain Criteria projectAnxiety disordersSocial processesMental Health's Research Domain Criteria projectNegative Valence Systems domainFronto-amygdala circuitryThreat learningPsychiatric disordersNegative valencePediatric anxietyChildren's fearsDevelopmental psychopathologyPrevalent psychiatric disordersParticular social processesAnxietyAttachment processRDoCResearch linksFearYouthTranslational approachDisordersInterdisciplinary approach