Featured Publications
Neural effects of controllability as a key dimension of stress exposure
Cohodes EM, Odriozola P, Mandell JD, Caballero C, McCauley S, Zacharek SJ, Hodges HR, Haberman JT, Smith M, Thomas J, Meisner OC, Ellis CT, Hartley CA, Gee DG. Neural effects of controllability as a key dimension of stress exposure. Development And Psychopathology 2022, 35: 218-227. PMID: 35034670, DOI: 10.1017/s0954579421001498.Peer-Reviewed Original ResearchConceptsDorsal anterior insulaRight dorsal anterior insulaUncontrollable stress conditionUncontrollable stressStress exposureSex-matched participantsStressor controllabilityInitial exposureFunctional magnetic resonance imaging (fMRI) acquisitionSubsequent stress exposureNeural effectsAnterior insulaYoung adultsSubsequent stressorsPatterns of activityCross-species evidenceNeural correlatesSubsequent exposureExposureNeural underpinningsPresent studyParticipantsMagnetic resonance imaging (MRI) acquisitionAdaptive responseFMRI analysis
2024
Responding to threat: Associations between neural reactivity to and behavioral avoidance of threat in pediatric anxiety
Kitt E, Zacharek S, Odriozola P, Nardini C, Hommel G, Martino A, Anderson T, Spencer H, Broussard A, Dean J, Marin C, Silverman W, Lebowitz E, Gee D. Responding to threat: Associations between neural reactivity to and behavioral avoidance of threat in pediatric anxiety. Journal Of Affective Disorders 2024, 351: 818-826. PMID: 38290579, PMCID: PMC10981528, DOI: 10.1016/j.jad.2024.01.204.Peer-Reviewed Original ResearchConceptsReactivity to threatMeasures of avoidanceVentral anterior insulaClinician-based measuresNeural reactivityPediatric anxietyAnxiety disordersBehavioral avoidanceFunctional magnetic resonance imaging taskAmygdala functional connectivityVentromedial prefrontal cortexTreatment-seeking sampleAvoidance of threatClinically significant constructsAssociated with tasksGeneralizability of findingsPrefrontal cortexAnterior insulaNeural findingsLaboratory tasksFunctional connectivityAnxietyAmygdalaAvoidanceSignificant constructs