2017
Ticks elicit variable fibrinogenolytic activities upon feeding on hosts with different immune backgrounds
Vora A, Taank V, Dutta SM, Anderson JF, Fish D, Sonenshine DE, Catravas JD, Sultana H, Neelakanta G. Ticks elicit variable fibrinogenolytic activities upon feeding on hosts with different immune backgrounds. Scientific Reports 2017, 7: 44593. PMID: 28300174, PMCID: PMC5353578, DOI: 10.1038/srep44593.Peer-Reviewed Original ResearchConceptsDifferent immune backgroundsImmune backgroundImmunodeficient animalsImmunocompetent animalsAge-matched miceAntibody-blocking assaysIxodes scapularis ticksFibrinogenolytic activityD-dimerAnti-hemostatic factorsImmune defenseTick feedingScapularis ticksReduced levelsBlood feedingEngorgement weightLC-MS/MSFibrinogenolysisNovel roleAnimalsPCR analysisTicksFeeding
2006
Modeling the Spatial Distribution of Mosquito Vectors for West Nile Virus in Connecticut, USA
Diuk-Wasser MA, Brown HE, Andreadis TG, Fish D. Modeling the Spatial Distribution of Mosquito Vectors for West Nile Virus in Connecticut, USA. Vector-Borne And Zoonotic Diseases 2006, 6: 283-295. PMID: 16989568, DOI: 10.1089/vbz.2006.6.283.Peer-Reviewed Original ResearchMyD88 Deficiency Enhances Acquisition and Transmission of Borrelia burgdorferi by Ixodes scapularis Ticks
Bockenstedt LK, Liu N, Schwartz I, Fish D. MyD88 Deficiency Enhances Acquisition and Transmission of Borrelia burgdorferi by Ixodes scapularis Ticks. Infection And Immunity 2006, 74: 2154-2160. PMID: 16552045, PMCID: PMC1418887, DOI: 10.1128/iai.74.4.2154-2160.2006.Peer-Reviewed Original ResearchConceptsMyD88-/- miceToll-like receptorsWT miceB. burgdorferiB. burgdorferi strainsInnate immune cellsBurgdorferi strainsSkin inoculation siteB. burgdorferi DNAHigh virulence strainDegree of infectivityIxodes scapularis ticksMyD88 deficiencyMolecule MyD88Immune cellsMore spirochetesTransmission of BorreliaEffector functionsHost immunityBorrelia burgdorferi strainsClinical isolatesPathogen burdenMiceBlood meal hostsScapularis ticks
2001
OspA Immunization Decreases Transmission of Borrelia burgdorferi Spirochetes from Infected Peromyscus leucopus Mice to Larval Ixodes scapularis Ticks
Tsao J, Barbour A, Luke C, Fikrig E, Fish D. OspA Immunization Decreases Transmission of Borrelia burgdorferi Spirochetes from Infected Peromyscus leucopus Mice to Larval Ixodes scapularis Ticks. Vector-Borne And Zoonotic Diseases 2001, 1: 65-74. PMID: 12653137, DOI: 10.1089/153036601750137705.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, WildAntibodies, BacterialAntigens, SurfaceArachnid VectorsBacterial Outer Membrane ProteinsBacterial VaccinesBorrelia burgdorferiDisease ReservoirsDose-Response Relationship, ImmunologicEnzyme-Linked Immunosorbent AssayFluorescent Antibody Technique, DirectHost-Parasite InteractionsIxodesLarvaLipoproteinsLyme DiseasePeromyscusConceptsControl miceUninfected larval ticksInfection prevalenceLarval Ixodes scapularis ticksB. burgdorferiNumber of spirochetesEnzyme-linked immunosorbentBorrelia burgdorferi spirochetesLevel of immunizationReservoir hostsConcentration of antibodyBorrelia burgdorferi transmissionIxodes scapularis ticksSecond vaccinationImmunized miceInfected miceLarval ticksPrior infectionVaccination programSubsequent riskDecrease transmissionOspA vaccinationDirect immunofluorescenceImmune responseXenodiagnostic ticks
1996
Duration of Tick Bites in a Lyme Disease-endemic Area
Falco R, Fish D, Piesman J. Duration of Tick Bites in a Lyme Disease-endemic Area. American Journal Of Epidemiology 1996, 143: 187-192. PMID: 8546120, DOI: 10.1093/oxfordjournals.aje.a008728.Peer-Reviewed Original Research
1993
Relative Importance of Bird Species as Hosts for Immature Ixodes dammini (Acari: Ixodidae) in a Suburban Residential Landscape of Southern New York State
Battaly G, Fish D. Relative Importance of Bird Species as Hosts for Immature Ixodes dammini (Acari: Ixodidae) in a Suburban Residential Landscape of Southern New York State. Journal Of Medical Entomology 1993, 30: 740-747. PMID: 8360897, DOI: 10.1093/jmedent/30.4.740.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, WildBirdsFemaleHost-Parasite InteractionsLarvaLyme DiseaseMaleNew YorkNymphPopulation DensitySpecies SpecificityTicksTime FactorsConceptsBird speciesAmerican robinsHouse wrenCommon gracklesAbundance of birdsBird density estimatesRelative density estimatesLyme disease spirochete Borrelia burgdorferi JohnsonAbundance dataQuiscalus quisculaTick parasitesBirdsSpeciesBorrelia burgdorferi JohnsonImportance valueGracklesWrenDensity estimatesRadius countsHostImmature Ixodes damminiLawnsLyme diseaseRelative importanceVieillot
1989
Host Associations of Ticks (Acari: Ixodidae) Parasitizing Medium-Sized Mammals in a Lyme Disease Endemic Area of Southern New York
Fish D, Dowler R. Host Associations of Ticks (Acari: Ixodidae) Parasitizing Medium-Sized Mammals in a Lyme Disease Endemic Area of Southern New York. Journal Of Medical Entomology 1989, 26: 200-209. PMID: 2724317, DOI: 10.1093/jmedent/26.3.200.Peer-Reviewed Original ResearchAnimalsArachnid VectorsFemaleHost-Parasite InteractionsLyme DiseaseMaleMammalsNew YorkTick InfestationsTicks