2009
Langerhans Cell Deficiency Impairs Ixodes scapularis Suppression of Th1 Responses in Mice
Vesely DL, Fish D, Shlomchik MJ, Kaplan DH, Bockenstedt LK. Langerhans Cell Deficiency Impairs Ixodes scapularis Suppression of Th1 Responses in Mice. Infection And Immunity 2009, 77: 1881-1887. PMID: 19273564, PMCID: PMC2681756, DOI: 10.1128/iai.00030-09.Peer-Reviewed Original ResearchConceptsTh1 responseTick salivaLangerhans cell subsetsLC-deficient miceSkin dendritic cellsTh1 immune responseTh cell polarizationTh cell responsesRegional lymph nodesT cell responsesTick feedingSecondary lymphoid organsGamma interferon productionSpleens of miceWild-type miceIxodes scapularis ticksT helperDendritic cellsLymph nodesLN cellsCell subsetsImmunomodulatory effectsLymphoid organsTh2 cellsImmune response
1993
Entomologic and demographic correlates of anti-tick saliva antibody in a prospective study of tick bite subjects in Westchester County, New York.
Schwartz B, Nadelman R, Fish D, Childs J, Forseter G, Wormser G. Entomologic and demographic correlates of anti-tick saliva antibody in a prospective study of tick bite subjects in Westchester County, New York. American Journal Of Tropical Medicine And Hygiene 1993, 48: 50-7. PMID: 8427388, DOI: 10.4269/ajtmh.1993.48.50.Peer-Reviewed Original ResearchConceptsSaliva antibodiesIndependent predictorsI. damminiLate-stage Lyme diseaseStrong independent predictorEnzyme-linked immunosorbentEngorgement indicesErythema migransProspective studyAntibody responseBiologic markersRisk factorsTick biteTick exposureNormal controlsSubject ageLogistic regressionLyme diseaseSalivary glandsOptical density valuesBiteTick engorgementConsistent changesDemographic correlatesAntibodies