Lyme disease ecology in a changing world: consensus, uncertainty and critical gaps for improving control
Kilpatrick AM, Dobson ADM, Levi T, Salkeld DJ, Swei A, Ginsberg HS, Kjemtrup A, Padgett KA, Jensen PM, Fish D, Ogden NH, Diuk-Wasser MA. Lyme disease ecology in a changing world: consensus, uncertainty and critical gaps for improving control. Philosophical Transactions Of The Royal Society B Biological Sciences 2017, 372: 20160117. PMID: 28438910, PMCID: PMC5413869, DOI: 10.1098/rstb.2016.0117.Peer-Reviewed Original ResearchConceptsNorth AmericaLyme disease ecologyDeer abundanceDifferent habitatsVector-borne zoonotic diseaseTemperate regionsDisease ecologyLyme disease preventionHost speciesDisease riskTick abundanceKnowledge gapsTemporal variationReservoir competenceCommon tick-borne diseaseEcologySubstantial uncertaintyAbundanceHost communitiesTick-borne diseaseTick populationsCritical gapAmericaAreas of consensusDisease preventionClosely-related Borrelia burgdorferi (sensu stricto) strains exhibit similar fitness in single infections and asymmetric competition in multiple infections
Rynkiewicz EC, Brown J, Tufts DM, Huang CI, Kampen H, Bent SJ, Fish D, Diuk-Wasser MA. Closely-related Borrelia burgdorferi (sensu stricto) strains exhibit similar fitness in single infections and asymmetric competition in multiple infections. Parasites & Vectors 2017, 10: 64. PMID: 28166814, PMCID: PMC5292797, DOI: 10.1186/s13071-016-1964-9.Peer-Reviewed Original ResearchConceptsAsymmetric competitive interactionsPatterns of coexistenceBiotic contextCommon disease vectorPathogen communitiesVector-borne pathogensBorrelia burgdorferiLong-term persistencePathogen speciesAsymmetric competitionPathogen dynamicsInfection phenotypesSimilar fitnessTransmission phenotypeDisease vectorsTemperate regionsCompetitive interactionsTransmission advantagePathogen strainsPathogen persistenceBlack-legged tickCompetitive strainsPeromyscus leucopusWhite-footed miceHost