Coinfection with Borrelia burgdorferi and the agent of human granulocytic ehrlichiosis suppresses IL‐2 and IFNγ production and promotes an IL‐4 response in C3H/HeJ mice
Zeidner N, Dolan M, Massung R, Piesman J, Fish D. Coinfection with Borrelia burgdorferi and the agent of human granulocytic ehrlichiosis suppresses IL‐2 and IFNγ production and promotes an IL‐4 response in C3H/HeJ mice. Parasite Immunology 2000, 22: 581-588. PMID: 11116438, DOI: 10.1046/j.1365-3024.2000.00339.x.Peer-Reviewed Original ResearchConceptsIL-4 productionIL-2Human granulocytic ehrlichiosisT cellsB. burgdorferiGranulocytic ehrlichiosisC3H/HeJ miceSplenic IL-4Systemic IL-2Th2 cytokine responsesIL-4 responsesIFN-gamma productionSplenic T cellsIFN-gamma responsesTick infestationHuman granulocytic ehrlichiosis (HGE) agentBorrelia burgdorferi transmissionIFNγ productionCytokine responsesIL-4HeJ miceGamma productionB cellsCoinfectionDay 10