2002
Magnetic Resonance Spectroscopic Studies of Neurotransmitters and Energy Metabolism in Epilepsy
Petroff O, Pan J, Rothman D. Magnetic Resonance Spectroscopic Studies of Neurotransmitters and Energy Metabolism in Epilepsy. Epilepsia 2002, 43: 40-50. DOI: 10.1046/j.1528-1157.2002.043s1040.x.Peer-Reviewed Original ResearchCerebral electrical activityGlutamate-glutamine cycleGABA synthesisGABA levelsRefractory complex partial seizuresOccipital GABA levelsLower GABA levelsCerebral energy stateComplex partial seizuresElectrical activityKetone body metabolismΓ-aminobutyric acid (GABA) metabolismHuman visual cortexCerebral excitabilityGlutamate reuptakePartial seizuresRefractory epilepsyGABAergic neuronsKetogenic dietBrain metabolismCortical excitabilitySynaptic glutamateBrain glutamateMyoclonic epilepsyNeurotransmitter pool
1991
Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation.
Prichard J, Rothman D, Novotny E, Petroff O, Kuwabara T, Avison M, Howseman A, Hanstock C, Shulman R. Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation. Proceedings Of The National Academy Of Sciences Of The United States Of America 1991, 88: 5829-5831. PMID: 2062861, PMCID: PMC51971, DOI: 10.1073/pnas.88.13.5829.Peer-Reviewed Original Research