Local recurrence versus new primary: Clinical analysis of 82 breast relapses and potential applications for genetic fingerprinting
Haffty B, Carter D, Flynn S, Fischer D, Brash D, Simons J, Ziegler A, Fischer J. Local recurrence versus new primary: Clinical analysis of 82 breast relapses and potential applications for genetic fingerprinting. International Journal Of Radiation Oncology • Biology • Physics 1993, 27: 575-583. PMID: 8226151, DOI: 10.1016/0360-3016(93)90382-6.Peer-Reviewed Original ResearchConceptsNew primary tumorsBreast relapsePrimary tumorTrue recurrenceNew primaryConservative surgeryLocal recurrencePathological criteriaRadiation therapyOriginal tumorSurvival rateClinical pathological analysisSecond primary tumorsShorter median timeTrue local recurrenceSignificant prognostic implicationsDNA flow cytometryLocal relapseMedian timePrognostic implicationsResidual diseaseTumor bedPathological analysisRelapseTherapeutic implications