2021
A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons
Ma Q, Srivastav SP, Gamez S, Dayama G, Feitosa-Suntheimer F, Patterson EI, Johnson RM, Matson EM, Gold AS, Brackney DE, Connor JH, Colpitts TM, Hughes GL, Rasgon JL, Nolan T, Akbari OS, Lau NC. A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons. Genome Research 2021, 31: gr.265157.120. PMID: 33419731, PMCID: PMC7919454, DOI: 10.1101/gr.265157.120.Peer-Reviewed Original ResearchConceptsPIWI-interacting RNAsGenomic resourcesMosquito cell culturesSmall RNA regulatory pathwaysSmall RNA expression profilesPIWI pathway genesRNA regulatory pathwaysSatellite DNA repeatsSmall RNA profilesCapacity of mosquitoesRNA interference (RNAi) pathwayRNA expression profilesImportant mosquito speciesTransposon activityGenome integritySiRNA populationsDNA repeatsInterference pathwayCluster lociCell culturesEvolutionary dynamicsPathway genesRegulatory pathwaysMosquito cellsExpression profiles
2008
Aedes aegyptiuses RNA interference in defense against Sindbis virus infection
Campbell C, Keene K, Brackney D, Olson K, Blair C, Wilusz J, Foy B. Aedes aegyptiuses RNA interference in defense against Sindbis virus infection. BMC Microbiology 2008, 8: 47. PMID: 18366655, PMCID: PMC2278134, DOI: 10.1186/1471-2180-8-47.Peer-Reviewed Original ResearchConceptsVirus-dependent mannerAgo2 protein levelsVirus-specific siRNAsAnti-viral defense mechanismProtein levelsSINV infectionRNAi componentsAnti-viral defenseRNAi pathwayRNAi responseBlood-fed controlsSmall RNAsDsRNA injectionRecombinant Sindbis virusRNA interferenceTranscript levelsSindbis virus infectionSINV RNAMost populationsStrand RNAPathway activitySINV replicationRNAVirus interactionsDefense mechanisms