2020
Worksite intervention study to prevent diabetes in Nepal: a randomised trial protocol
Pyakurel P, Shrestha A, Karmacharya BM, Budhathoki SS, Chaudhari RK, Tamrakar D, Shrestha A, Karmacharya RM, Shrestha A, Sharma S, Sharma SK, Spiegelman D. Worksite intervention study to prevent diabetes in Nepal: a randomised trial protocol. Open Heart 2020, 7: e001236. PMID: 32847993, PMCID: PMC7451278, DOI: 10.1136/openhrt-2019-001236.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomarkersBlood GlucoseDiabetes MellitusGlycated HemoglobinHealth BehaviorHealth Knowledge, Attitudes, PracticeHealthy LifestyleHumansMaleMiddle AgedMulticenter Studies as TopicNepalOccupational Health ServicesPatient Education as TopicPrediabetic StatePrimary PreventionRandomized Controlled Trials as TopicRisk Reduction BehaviorTime FactorsTreatment OutcomeConceptsBehavioral interventionsControl periodDiabetes risk reductionMonth control periodNepal Health Research CouncilBehavioral intervention groupWorksite intervention studiesT-testHealth Research CouncilInstitutional review boardTwo-sample t-testBlood sugarTrial protocolIntervention groupEthical approvalControl groupIntervention studiesType 2More monthsReview boardInterventionDiabetesParticipant changesPublic healthRisk reduction
2019
Substituting brown rice for white rice on diabetes risk factors in India: a randomised controlled trial
Malik V, Sudha V, Wedick N, RamyaBai M, Vijayalakshmi P, Lakshmipriya N, Gayathri R, Kokila A, Jones C, Hong B, Li R, Krishnaswamy K, Anjana R, Spiegelman D, Willett W, Hu F, Mohan V. Substituting brown rice for white rice on diabetes risk factors in India: a randomised controlled trial. British Journal Of Nutrition 2019, 121: 1389-1397. PMID: 31006420, PMCID: PMC6948352, DOI: 10.1017/s000711451900076x.Peer-Reviewed Original ResearchConceptsBrown rice groupMetabolic syndromePrimary outcomeRisk factorsHigh-sensitivity C-reactive proteinRandomised cross-over trialT2D risk factorsDiabetes risk factorsC-reactive proteinCross-over trialType 2 diabetesWhite rice groupMeals/dHs-CRPSecondary outcomesElevated BMIWashout periodInsulin resistanceBlood glucoseEpidemiological evidenceWhite riceT2D riskUrban South IndiaBMISyndrome
2003
Alcohol Consumption Patterns and HbA1c, C-Peptide and Insulin Concentrations in Men
Meyer KA, Conigrave KM, Chu NF, Rifai N, Spiegelman D, Stampfer MJ, Rimm EB. Alcohol Consumption Patterns and HbA1c, C-Peptide and Insulin Concentrations in Men. Journal Of The American Nutrition Association 2003, 22: 185-194. PMID: 12805244, DOI: 10.1080/07315724.2003.10719292.Peer-Reviewed Original ResearchConceptsC-peptideInsulin concentrationsAverage alcohol consumptionAlcohol consumptionAlcohol consumption patternsBlood samplesStudy participantsDrinking patternsDisease-free menC-peptide concentrationsModerate alcohol consumptionCross-sectional studyYears of ageFrequent alcohol consumptionFrequency of consumptionEffects of alcoholInsulin levelsBiologic markersInsulin sensitivityInverse associationAverage daily consumptionIrregular drinkersObservational studyAnalysis of insulinHealth professionals
2000
Glycemic status and soluble tumor necrosis factor receptor levels in relation to plasma leptin concentrations among normal weight and overweight US men
Chu N, Spiegelman D, Rifai N, Hotamisligil G, Rimm E. Glycemic status and soluble tumor necrosis factor receptor levels in relation to plasma leptin concentrations among normal weight and overweight US men. International Journal Of Obesity 2000, 24: 1085-1092. PMID: 11033975, DOI: 10.1038/sj.ijo.0801361.Peer-Reviewed Original ResearchConceptsPlasma leptinSTNF-R1C-peptideOverweight menGlycemic statusLeptin concentrationsGlucose homeostasisSoluble tumor necrosis factor receptor levelsSoluble tumour necrosis factor receptor concentrationsTumor necrosis factor receptor levelsDetailed lifestyle questionnaireSTNF-R2 concentrationsHealth Professionals FollowBody mass indexPlasma leptin levelsObesity-related disordersAdipose-derived cytokineCross-sectional studyConsiderable inter-individual variationProfessionals FollowDiabetes mellitusLeptin levelsMass indexNormal weightHighest quintile