2005
A Comparison of the Clinical and Cost-Effectiveness of 3 Intervention Strategies for AIDS Wasting
Shevitz AH, Wilson IB, McDermott AY, Spiegelman D, Skinner SC, Antonsson K, Layne JE, Beaston-Blaakman A, Shepard DS, Gorbach SL. A Comparison of the Clinical and Cost-Effectiveness of 3 Intervention Strategies for AIDS Wasting. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2005, 38: 399-406. PMID: 15764956, DOI: 10.1097/01.qai.0000152647.89008.2b.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnabolic AgentsAntiretroviral Therapy, Highly ActiveBody CompositionCost-Benefit AnalysisDietFemaleHealth StatusHIV Wasting SyndromeHumansMaleMassachusettsMiddle AgedMuscle, SkeletalNutritional Physiological PhenomenaOxandrolonePhysical Education and TrainingQuality of LifeTreatment OutcomeConceptsProgressive resistance trainingCross-sectional muscle areaPhysical functioningCost-effective interventionAIDS wastingLeast cost-effective interventionBaseline physical functioningQuality of lifeInstitutional costsPlacebo pillsResistance trainingCaloric intakeProtein intakeBody compositionStrength training
2004
Sexual Orientation, Health Risk Factors, and Physical Functioning in the Nurses' Health Study II
Case P, Austin SB, Hunter DJ, Manson JE, Malspeis S, Willett WC, Spiegelman D. Sexual Orientation, Health Risk Factors, and Physical Functioning in the Nurses' Health Study II. Journal Of Women's Health 2004, 13: 1033-1047. PMID: 15665660, DOI: 10.1089/jwh.2004.13.1033.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingBisexualityBody Mass IndexBreast NeoplasmsCardiovascular DiseasesCross-Sectional StudiesDepressionFemaleHealth BehaviorHealth StatusHomosexuality, FemaleHumansLinear ModelsMental HealthMiddle AgedMultivariate AnalysisNurse CliniciansPrevalenceProspective StudiesRisk FactorsSmokingTime FactorsUnited StatesConceptsNurses' Health Study IIHealth Study IIBody mass indexRisk factorsHealth risk factorsHigh prevalenceRegion of residenceOverall cohortBreast cancerHealth statusHigher daily alcohol intakeCardiovascular disease risk factorsBreast cancer risk factorsHigher body mass indexStudy IIMultivariate prevalence ratiosDaily alcohol intakeDisease risk factorsUse of antidepressantsCancer risk factorsHealth-related functioningImportant risk factorMental health statusPoor mental healthBisexual women
2002
Changes in lean body mass and total body weight are weakly associated with physical functioning in patients with HIV infection
Wilson I, Jacobson D, Roubenoff R, Spiegelman D, Knox T, Gorbach S. Changes in lean body mass and total body weight are weakly associated with physical functioning in patients with HIV infection. HIV Medicine 2002, 3: 263-270. PMID: 12444944, DOI: 10.1046/j.1468-1293.2002.00122.x.Peer-Reviewed Original ResearchConceptsTotal body weightSelf-reported physical functioningPhysical functioningHIV infectionBody weightRelationship of changesCells/ micro l.Mean CD4 countHIV-positive personsMain outcome measuresLean body massLongitudinal analysisCD4 countCohort studyPositive personsOutcome measuresHealthy personsBody compositionPatientsStudy designWeight lossMicro l.InfectionWomenHealthy living
2000
Predictors of Change in the Functional Status of Children With Human Immunodeficiency Virus Infection
Missmer S, Spiegelman D, Gorbach S, Miller T. Predictors of Change in the Functional Status of Children With Human Immunodeficiency Virus Infection. Pediatrics 2000, 106: e24-e24. PMID: 10920180, DOI: 10.1542/peds.106.2.e24.Peer-Reviewed Original ResearchConceptsHeight z-scoreHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionTotal health scoreFunctional statusHealth scoresZ-scoreGeneral healthVirus infectionBaseline evaluationCD4 T-lymphocyte countFunctional status parametersFunctional status surveyHIV disease stageT-lymphocyte countsAbsolute CD4 countGeneral health scoresImportant clinical predictorsSignificant univariate predictorsFunctional status scoresMain outcome measuresNon-white raceResponsiveness scoresPredictors of changeCD4 countAdiposity and Mortality in Men
Baik I, Ascherio A, Rimm EB, Giovannucci E, Spiegelman D, Stampfer MJ, Willett WC. Adiposity and Mortality in Men. American Journal Of Epidemiology 2000, 152: 264-271. PMID: 10933273, DOI: 10.1093/aje/152.3.264.Peer-Reviewed Original ResearchConceptsBody mass indexRecent weight lossMeasures of adiposityCardiovascular diseaseGreater body mass indexWeight lossCardiovascular disease mortalityRisk of deathCancer mortality riskCause-specific mortalityExclusion of menLean menOverall mortalityWaist circumferenceMass indexDisease mortalityExcess mortalityRelative riskBody fatMortality riskUS menElevated riskOlder menHigh mortalityMortalityRelation of Lean Body Mass to Health-Related Quality of Life in Persons With HIV
Wilson I, Roubenoff R, Knox T, Spiegelman D, Gorbach S. Relation of Lean Body Mass to Health-Related Quality of Life in Persons With HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 24: 137-146. DOI: 10.1097/00042560-200006010-00008.Peer-Reviewed Original ResearchConceptsLean body massHigher lean body massGeneral health perceptionEnergy/fatiguePhysical functioningHealth perceptionBetter general health perceptionBioimpedance analysisDesign Cross-sectional analysisMeasures of HRQLHealth-related qualityBody massLast monthBetter physical functioningQuality of lifeCross-sectional analysisCD4 countHIV infectionMean ageClinical impactMultivariable modelHIVCells/Number of daysWomenRelation of lean body mass to health-related quality of life in persons with HIV.
Wilson I, Roubenoff R, Knox T, Spiegelman D, Gorbach S. Relation of lean body mass to health-related quality of life in persons with HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 24: 137-46. PMID: 10935689, DOI: 10.1097/00126334-200006010-00008.Peer-Reviewed Original ResearchConceptsGeneral health perceptionPhysical functionHealth-related qualityLean body massHigher lean body massHealth perceptionAssociated with better physical functionClinical impact of interventionsHealth-related quality of lifeDiverse population of personsBioimpedance analysisPatient self-reportBody massImpact of interventionsPopulation of personsCross-sectional analysisQuality of lifeIncreased LBMSelf-reportDiverse populationsEnergy/fatigueMultivariate modelHIVCD4 countHIV infection