Early access to antiretroviral therapy versus standard of care among HIV‐positive participants in Eswatini in the public health sector: the MaxART stepped‐wedge randomized controlled trial
Khan S, Spiegelman D, Walsh F, Mazibuko S, Pasipamire M, Chai B, Reis R, Mlambo K, Delva W, Khumalo G, Zwane M, Fleming Y, Mafara E, Hettema A, Lejeune C, Chao A, Bärnighausen T, Okello V. Early access to antiretroviral therapy versus standard of care among HIV‐positive participants in Eswatini in the public health sector: the MaxART stepped‐wedge randomized controlled trial. Journal Of The International AIDS Society 2020, 23: e25610. PMID: 32949103, PMCID: PMC7507004, DOI: 10.1002/jia2.25610.Peer-Reviewed Original ResearchConceptsViral suppressionStandard of careAntiretroviral treatmentCox proportional hazards modelHealth systemART-naïve participantsHIV-positive patientsHIV-positive adultsViral load monitoringHIV-positive participantsAppropriate care managementProportional hazards modelEarly accessPublic sector health facilitiesHealth system effectsPublic health systemHealth system's abilityClinic transitionAntiretroviral therapyCD4 countCare retentionVL monitoringPublic health sectorDisease stageEndpoint rateImpact of the Affordable Care Act on Colorectal Cancer Outcomes: A Systematic Review
Xu MR, Kelly AMB, Kushi LH, Reed ME, Koh HK, Spiegelman D. Impact of the Affordable Care Act on Colorectal Cancer Outcomes: A Systematic Review. American Journal Of Preventive Medicine 2020, 58: 596-603. PMID: 32008799, PMCID: PMC7175922, DOI: 10.1016/j.amepre.2019.11.018.Peer-Reviewed Original ResearchConceptsColorectal cancer screeningAffordable Care ActCancer screeningMedicaid expansionColorectal cancerCare ActNonsignificant increaseColorectal cancer morbidityColorectal cancer outcomesColorectal cancer incidenceStage of diagnosisAffordable Care Act's impactScreening ratesCancer outcomesCancer morbidityPrecancerous lesionsCancer incidenceNonsignificant decreaseEarly diagnosisMortality rateHealth outcomesSystematic reviewHealthcare accessRelevant studiesSignificant decrease