Risk factors for adult T-cell leukemia among carriers of human T-lymphotropic virus type I.
Hisada M, Okayama A, Shioiri S, Spiegelman D, Stuver S, Mueller N. Risk factors for adult T-cell leukemia among carriers of human T-lymphotropic virus type I. Blood 1998, 92: 3557-61. PMID: 9808547, DOI: 10.1182/blood.v92.10.3557.422k09_3557_3561.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge of OnsetAgedAged, 80 and overBiomarkers, TumorCarrier StateCohort StudiesFemaleGene Products, taxHTLV-I AntibodiesHTLV-I InfectionsHuman T-lymphotropic virus 1HumansJapanLeukemia-Lymphoma, Adult T-CellMaleMiddle AgedNeoplastic Stem CellsProspective StudiesRisk FactorsSmokingT-LymphocytesConceptsAdult T-cell leukemiaHTLV-I carriersT-cell leukemiaAsymptomatic HTLV-I carriersHuman T-lymphotropic virus type IHuman T-lymphotropic virus type I.Miyazaki Cohort StudyHTLV-I antibodiesVirus type IAbnormal lymphocytesCohort studyViral markersATL diagnosisRisk factorsLow prevalenceFlower cellsATL casesGreater riskHTLVAntibodiesPositive controlType I.LeukemiaRegulatory proteinsType IPredictors of level of circulating abnormal lymphocytes among human T‐lymphotropic virus type I carriers in Japan
Hisada M, Okayama A, Tachibana N, Stuver S, Spiegelman D, Tsubouchi H, Mueller N. Predictors of level of circulating abnormal lymphocytes among human T‐lymphotropic virus type I carriers in Japan. International Journal Of Cancer 1998, 77: 188-192. PMID: 9650550, DOI: 10.1002/(sici)1097-0215(19980717)77:2<188::aid-ijc3>3.0.co;2-m.Peer-Reviewed Original ResearchConceptsHuman T-lymphotropic virus type I carriersAdult T-cell leukemiaHigh proviral loadAbnormal lymphocytesProviral loadI carriersAsymptomatic HTLV-I carriersHTLV-I carriersT-cell leukemiaMale genderMultivariate analysisMalignant cellsBlood smearsPredictors of levelsLongitudinal studyLymphocytesPredictorsHTLVLeukemiaLevelsSmears