Polymorphic repeat in AIB1 does not alter breast cancer risk
Haiman C, Hankinson S, Spiegelman D, Colditz G, Willett W, Speizer F, Brown M, Hunter D. Polymorphic repeat in AIB1 does not alter breast cancer risk. Breast Cancer Research 2000, 2: 378. PMID: 11056690, PMCID: PMC13920, DOI: 10.1186/bcr82.Peer-Reviewed Original ResearchConceptsBreast cancer riskHealth Study cohortCancer riskPostmenopausal breast cancer riskNurses' Health Study cohortBreast cancer incidenceCase-control studySpecific tumor characteristicsAIB1 genotypeStudy cohortTumor characteristicsCancer incidenceCaucasian womenGeneral populationAIB1Repeat polymorphismRiskAssociationCohortIncidenceGenotypesWomenA tetranucleotide repeat polymorphism in CYP19 and breast cancer risk
Haiman C, Hankinson S, Spiegelman D, De Vivo I, Colditz G, Willett W, Speizer F, Hunter D. A tetranucleotide repeat polymorphism in CYP19 and breast cancer risk. International Journal Of Cancer 2000, 87: 204-210. PMID: 10861475, DOI: 10.1002/1097-0215(20000715)87:2<204::aid-ijc8>3.0.co;2-3.Peer-Reviewed Original ResearchConceptsBreast cancer riskHealth Study cohortCase-control studyCancer riskHormone levelsNurses' Health Study cohortBreast cancer case-control studyElevated estrogen levelsAdvanced cancer casesCancer case-control studyRepeat polymorphismTetranucleotide repeat polymorphismConversion of androgensGreater frequencyKey steroidogenic enzymesSignificant greater frequencyDistant metastasisStudy cohortEstrogen levelsCYP19 allelesBreast cancerCancer casesAllele carriersEstrone sulfateNonsignificant increase