Randomised trial of effects of vitamin supplements on pregnancy outcomes and T cell counts in HIV-1-infected women in Tanzania
Fawzi W, Msamanga G, Spiegelman D, Urassa E, McGrath N, Mwakagile D, Antelman G, Mbise R, Kapiga S, Willett W, Hunter D, Team F, Herrera G. Randomised trial of effects of vitamin supplements on pregnancy outcomes and T cell counts in HIV-1-infected women in Tanzania. The Lancet 1998, 351: 1477-1482. PMID: 9605804, DOI: 10.1016/s0140-6736(98)04197-x.Peer-Reviewed Original ResearchConceptsHIV-1-infected womenT-cell countsHIV-1 diseaseBirth outcomesVitamin APregnancy outcomesMultivitamin supplementationHIV-1-infected pregnant womenPoor micronutrient statusTrial of effectAdverse pregnancy outcomesPlacebo-controlled trialT lymphocyte subsetsAdverse birth outcomesEffects of multivitaminsSevere preterm birthsLymphocyte subsetsPreterm birthFetal deathWeeks' gestationGestational ageClinical progressionPregnant womenLow birthweightFaster progression