2022
Anemia Etiology in Ethiopia: Assessment of Nutritional, Infectious Disease, and Other Risk Factors in a Population-Based Cross-Sectional Survey of Women, Men, and Children
Andersen CT, Tadesse AW, Bromage S, Fekadu H, Hemler EC, Passarelli S, Spiegelman D, Sudfeld CR, Worku A, Berhane Y, Fawzi WW. Anemia Etiology in Ethiopia: Assessment of Nutritional, Infectious Disease, and Other Risk Factors in a Population-Based Cross-Sectional Survey of Women, Men, and Children. Journal Of Nutrition 2022, 152: 501-512. PMID: 34647598, PMCID: PMC8990104, DOI: 10.1093/jn/nxab366.Peer-Reviewed Original ResearchConceptsRisk factorsAnemia casesPopulation-based cross-sectional studyFolic acid food fortificationC-reactive protein levelsInfectious diseasesPopulation attributable risk percentageVitamin B12Proportion of anemiaDietary iron intakeCause of anemiaHelminth infection statusAttributable risk percentageLow serum ferritinLow serum folateVenous blood samplesPopulation-weighted prevalenceCross-sectional studyPublic health interventionsPotential public health interventionsCross-sectional surveyAssessment of NutritionalIron interventionsSerum ferritinAnemia etiology
2017
Prevalence estimation when disease status is verified only among test positives: Applications in HIV screening programs
Thomas E, Peskoe S, Spiegelman D. Prevalence estimation when disease status is verified only among test positives: Applications in HIV screening programs. Statistics In Medicine 2017, 37: 1101-1114. PMID: 29230839, PMCID: PMC6512805, DOI: 10.1002/sim.7568.Peer-Reviewed Original Research
2012
Predictors of stunting, wasting and underweight among Tanzanian children born to HIV-infected women
McDonald CM, Kupka R, Manji KP, Okuma J, Bosch RJ, Aboud S, Kisenge R, Spiegelman D, Fawzi WW, Duggan CP. Predictors of stunting, wasting and underweight among Tanzanian children born to HIV-infected women. European Journal Of Clinical Nutrition 2012, 66: 1265-1276. PMID: 23031850, PMCID: PMC3491141, DOI: 10.1038/ejcn.2012.136.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBody HeightBody WeightDouble-Blind MethodEducational StatusFemaleGrowth DisordersHIV InfectionsHumansInfantInfant, Low Birth WeightInfant, NewbornInfant, PrematureInfectious Disease Transmission, VerticalMaleMalnutritionPremature BirthPrevalenceProportional Hazards ModelsReference ValuesSex FactorsSocioeconomic FactorsTanzaniaThinnessWasting SyndromeYoung AdultConceptsBirth weightFirst episodeTanzanian childrenMultivariate Cox proportional hazards methodMaternal educationLow infant birth weightCox proportional hazards methodDevelopment of undernutritionInfant birth weightLow Apgar scoreModifiable risk factorsLow birth weightChild HIV infectionHuman immunodeficiency virusPredictors of stuntingRisk of undernutritionProportional hazards methodsLow maternal educationWeeks of ageMorbidity historiesApgar scoreChild transmissionMedian durationPreterm infantsHIV infectionElevated alanine aminotransferase in antiretroviral‐naïve HIV‐infected African patients: magnitude and risk factors
Nagu T, Kanyangarara M, Hawkins C, Hertmark E, Chalamila G, Spiegelman D, Mugusi F, Fawzi W. Elevated alanine aminotransferase in antiretroviral‐naïve HIV‐infected African patients: magnitude and risk factors. HIV Medicine 2012, 13: 541-548. PMID: 22416813, PMCID: PMC3391335, DOI: 10.1111/j.1468-1293.2012.01006.x.Peer-Reviewed Original ResearchConceptsElevated alanine aminotransferaseIU/LAlanine aminotransferaseAntiretroviral therapyHigh riskWorld Health Organization clinical stageCD4 T-lymphocyte countFirst-line antiretroviral therapyHepatitis B virus coinfectionALT measurementsLow-density lipoprotein cholesterolLog-binomial regression modelsB virus coinfectionT-lymphocyte countsART-naïve HIVCells/μLHepatotoxic side effectsCurrent tuberculosis (TB) treatmentResource-limited settingsCross-sectional analysisAdvanced immunosuppressionHBV coinfectionART-naïveHIV careLipoprotein cholesterol
2010
Lipid-soluble vitamins A, D, and E in HIV-infected pregnant women in Tanzania
Mehta S, Spiegelman D, Aboud S, Giovannucci EL, Msamanga GI, Hertzmark E, Mugusi FM, Hunter DJ, Fawzi WW. Lipid-soluble vitamins A, D, and E in HIV-infected pregnant women in Tanzania. European Journal Of Clinical Nutrition 2010, 64: 808-817. PMID: 20517330, PMCID: PMC3078753, DOI: 10.1038/ejcn.2010.76.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnemia, Iron-DeficiencyAvitaminosisBlood SedimentationCD8-Positive T-LymphocytesCell CountDietFemaleGestational AgeHemoglobinsHIV InfectionsHumansNutritional StatusPregnancyPrevalenceRegression AnalysisSeleniumTanzaniaVitamin AVitamin A DeficiencyVitamin DVitamin D DeficiencyVitamin EVitamin E DeficiencyYoung AdultConceptsErythrocyte sedimentation rateVitamin E statusPregnant womenLipid-soluble vitaminsVitamin APlasma vitaminGestational ageLow vitaminE statusLow vitamin D statusHigh erythrocyte sedimentation rateLow vitamin E statusLipid-soluble vitamins ACD8 cell countsVitamin D statusHuman immunodeficiency virusPlasma vitamin EPoor nutritional statusPlasma vitamin ALow plasma vitamin AResource-limited settingsD statusLaboratory parametersImmunodeficiency virusSevere anemia
2007
Point and interval estimates of partial population attributable risks in cohort studies: examples and software
Spiegelman D, Hertzmark E, Wand HC. Point and interval estimates of partial population attributable risks in cohort studies: examples and software. Cancer Causes & Control 2007, 18: 571-579. PMID: 17387622, DOI: 10.1007/s10552-006-0090-y.Peer-Reviewed Original ResearchConceptsCohort studyRisk factorsPartial population attributable riskNon-modifiable risk factorsSpecific exposuresPopulation attributable risk percentAttributable risk percentPopulation attributable riskBladder cancer incidenceGroups of exposureTarget populationProportion of diseaseAttributable riskDisease burdenModifiable determinantsCancer incidencePublic health researchDiseaseHealth researchExposurePopulationIncidenceProportion
2006
Socio-economic and demographic factors associated with prevalence of HIV infection among pregnant women in Dar es Salaam, Tanzania
Msamanga G, Fawzi W, Hertzmark E, McGrath N, Kapiga S, Kagoma C, Spiegelman D, Hunter D. Socio-economic and demographic factors associated with prevalence of HIV infection among pregnant women in Dar es Salaam, Tanzania. East African Medical Journal 2006, 83: 311-321. PMID: 16989376, DOI: 10.4314/eamj.v83i6.9438.Peer-Reviewed Original ResearchConceptsHIV infectionAntenatal clinicHIV-1-positive womenDar es SalaamMaternal-foetal transmissionMid-arm circumferenceHIV-1 infectionDemographic characteristicsLow HIV prevalenceCross-sectional studyHIV prevalence ratesHIV/AIDS epidemicOpt-out approachLow-resource settingsPositive womenNevirapine treatmentHIV prevalencePregnant womenMaternal ageHigh prevalenceRegular partnersPrevalence ratesPartner's occupationTanzanian womenOlder age
2005
Easy SAS Calculations for Risk or Prevalence Ratios and Differences
Spiegelman D, Hertzmark E. Easy SAS Calculations for Risk or Prevalence Ratios and Differences. American Journal Of Epidemiology 2005, 162: 199-200. PMID: 15987728, DOI: 10.1093/aje/kwi188.Peer-Reviewed Original ResearchCalculating deaths attributable to obesity.
Hu FB, Willett WC, Stampfer MJ, Spiegelman D, Colditz GA. Calculating deaths attributable to obesity. American Journal Of Public Health 2005, 95: 932; author reply 932-3. PMID: 15914810, PMCID: PMC1449281, DOI: 10.2105/ajph.2005.062836.Peer-Reviewed Original ResearchPrevalence of, Evolution of, and Risk Factors for Fat Atrophy and Fat Deposition in a Cohort of HIV-Infected Men and Women
Jacobson DL, Knox T, Spiegelman D, Skinner S, Gorbach S, Wanke C. Prevalence of, Evolution of, and Risk Factors for Fat Atrophy and Fat Deposition in a Cohort of HIV-Infected Men and Women. Clinical Infectious Diseases 2005, 40: 1837-1845. PMID: 15909274, DOI: 10.1086/430379.Peer-Reviewed Original ResearchConceptsFat atrophyRisk factorsFat depositionBaseline prevalenceCentral fat depositionHIV-Infected MenActive antiretroviral therapyHigh triglyceride levelsHuman immunodeficiency virusNutrition Examination SurveyPercent of subjectsSkin-fold measurementsBody fat levelsAbacavir useHIV loadStavudine useAntiretroviral therapyHip ratioImmunodeficiency virusExamination SurveyTriglyceride levelsNational HealthHigh school educationSmaller hipIndependent syndromeHigh school dietary dairy intake and teenage acne
Adebamowo CA, Spiegelman D, Danby FW, Frazier AL, Willett WC, Holmes MD. High school dietary dairy intake and teenage acne. Journal Of The American Academy Of Dermatology 2005, 52: 207-214. PMID: 15692464, DOI: 10.1016/j.jaad.2004.08.007.Peer-Reviewed Original ResearchConceptsTeenage acnePrevalence ratiosNurses' Health Study IIDietary dairy intakeHigh school dietMultivariate prevalence ratiosHealth Study IIBody mass indexCategories of intakeLow-fat milkMass indexSchool dietDairy intakeWestern dietPresence of hormoneAcne historyPossible associationAcneEnergy intakeStudy IIIntakeBreakfast drinksConfidence intervalsTotal milkDairy foods
2004
Sexual Orientation, Health Risk Factors, and Physical Functioning in the Nurses' Health Study II
Case P, Austin SB, Hunter DJ, Manson JE, Malspeis S, Willett WC, Spiegelman D. Sexual Orientation, Health Risk Factors, and Physical Functioning in the Nurses' Health Study II. Journal Of Women's Health 2004, 13: 1033-1047. PMID: 15665660, DOI: 10.1089/jwh.2004.13.1033.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingBisexualityBody Mass IndexBreast NeoplasmsCardiovascular DiseasesCross-Sectional StudiesDepressionFemaleHealth BehaviorHealth StatusHomosexuality, FemaleHumansLinear ModelsMental HealthMiddle AgedMultivariate AnalysisNurse CliniciansPrevalenceProspective StudiesRisk FactorsSmokingTime FactorsUnited StatesConceptsNurses' Health Study IIHealth Study IIBody mass indexRisk factorsHealth risk factorsHigh prevalenceRegion of residenceOverall cohortBreast cancerHealth statusHigher daily alcohol intakeCardiovascular disease risk factorsBreast cancer risk factorsHigher body mass indexStudy IIMultivariate prevalence ratiosDaily alcohol intakeDisease risk factorsUse of antidepressantsCancer risk factorsHealth-related functioningImportant risk factorMental health statusPoor mental healthBisexual womenRisk of uterine leiomyomata in relation to tobacco, alcohol and caffeine consumption in the Black Women's Health Study
Wise LA, Palmer JR, Harlow BL, Spiegelman D, Stewart EA, Adams-Campbell LL, Rosenberg L. Risk of uterine leiomyomata in relation to tobacco, alcohol and caffeine consumption in the Black Women's Health Study. Human Reproduction 2004, 19: 1746-1754. PMID: 15218005, PMCID: PMC1876785, DOI: 10.1093/humrep/deh309.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosBlack Women's Health StudyWomen's Health StudyUterine leiomyomataHealth StudyCaffeine consumptionCigarette smokingMultivariate incidence rate ratiosSelf-reported uterine leiomyomataDrinks/weekConfidence intervalsUS black womenHeavy coffeePremenopausal womenIncident casesOvarian functionLeiomyomataAlcohol consumptionRate ratioHormone metabolismWomenSmokingRiskBeer consumptionBlack women
2002
HIV status and sociodemographic correlates of maternal body size and wasting during pregnancy
Villamor E, Msamanga G, Spiegelman D, Coley J, Hunter D, Peterson K, Fawzi W. HIV status and sociodemographic correlates of maternal body size and wasting during pregnancy. European Journal Of Clinical Nutrition 2002, 56: 415-424. PMID: 12001012, DOI: 10.1038/sj.ejcn.1601328.Peer-Reviewed Original ResearchConceptsWeeks of gestationHIV infectionHIV statusPregnant womenFirst prenatal visitSocioeconomic statusSignificant risk factorsCross-sectional studyLow socioeconomic statusLevel of educationMean MUACAntenatal clinicMaternal heightPrenatal visitUninfected mothersSecond trimesterMaternal ageOverall prevalenceRisk factorsChild healthMother's ageMultivariate analysisFogarty International CenterSociodemographic correlatesBMI
2001
The association between maternal HIV‐1 infection and pregnancy outcomes in Dar es Salaam, Tanzania
Coley J, Msamanga G, Fawzi M, Kaaya S, Hertzmark E, Kapiga S, Spiegelman D, Hunter D, Fawzi W. The association between maternal HIV‐1 infection and pregnancy outcomes in Dar es Salaam, Tanzania. BJOG An International Journal Of Obstetrics & Gynaecology 2001, 108: 1125-1133. PMID: 11762650, PMCID: PMC6276363, DOI: 10.1111/j.1471-0528.2003.00269.x.Peer-Reviewed Original ResearchConceptsAdverse pregnancy outcomesPregnancy outcomesSymptomatic HIVLow birthweightPregnant womenHigh riskMaternal HIV-1 infectionMaternal HIV infectionCohort of HIVProspective cohort studyHIV-1 infectionWeeks of gestationPotential confounding factorsDar es SalaamCohort studyHIV infectionGestational ageImmature infantsFetal lossHead circumferenceHIVConfounding factorsWomenOutcomesSignificant differencesAssessment of Markers of Hepatitis C Virus Infection in a Japanese Adult Population
Arduino J, Stuver S, Spiegelman D, Okayama A, Tabor E, Yu M, Kohara M, Tsubouchi H, Mueller N. Assessment of Markers of Hepatitis C Virus Infection in a Japanese Adult Population. The Journal Of Infectious Diseases 2001, 184: 1229-1235. PMID: 11679910, DOI: 10.1086/324006.Peer-Reviewed Original ResearchConceptsHepatitis C virus infectionC virus infectionHCV core proteinHCV infectionHCV RNAVirus infectionCommunity-based Japanese populationCurrent HCV infectionHCV infection statusLatent class analysisJapanese adult populationLogistic regression analysisAssessment of markersUsefulness of markersVirus markersCore proteinAdult populationInfectionInfection statusSerum samplesJapanese populationHCVRegression analysisDemographic factorsMarkersValidation of the Gail et al. Model of Breast Cancer Risk Prediction and Implications for Chemoprevention
Rockhill B, Spiegelman D, Byrne C, Hunter D, Colditz G. Validation of the Gail et al. Model of Breast Cancer Risk Prediction and Implications for Chemoprevention. Journal Of The National Cancer Institute 2001, 93: 358-366. PMID: 11238697, DOI: 10.1093/jnci/93.5.358.Peer-Reviewed Original ResearchConceptsInvasive breast cancerGail et alRisk factor strataBreast cancerDiscriminatory accuracyHealth StudyModest discriminatory accuracyNurses' Health StudySubset of womenBreast cancer casesBreast cancer risk predictionNet health benefitCancer risk predictionTamoxifen useCancer casesPrevention optionsConcordance statisticClinical counselingCancerYoung womenWhite womenRisk estimatesWomenHealth benefitsRisk prediction
2000
Diarrhea and abnormalities of gastrointestinal function in a cohort of men and women with HIV infection
Knox T, Spiegelman D, Skinner S, Gorbach S. Diarrhea and abnormalities of gastrointestinal function in a cohort of men and women with HIV infection. The American Journal Of Gastroenterology 2000, 95: ajg20001597. PMID: 11151881, DOI: 10.1111/j.1572-0241.2000.03365.x.Peer-Reviewed Original ResearchConceptsIntravenous drug usersD-xylose absorptionLow D-xylose absorptionVitamin B12 levelsGastrointestinal functionHIV infectionLiver diseaseStool pathogensGastrointestinal dysfunctionB12 levelsLow serum vitamin B12 levelsLow vitamin B12 levelsSerum vitamin B12 levelsSeverity of immunosuppressionSudan III stainCells/mm3D-xylose testAbsence of diarrheaCohort of menAdvanced immunosuppressionCurrent diarrheaChronic diarrheaSerum levelsHIV treatmentFat dietNutritional Factors and Infectious Disease Contribute to Anemia among Pregnant Women with Human Immunodeficiency Virus in Tanzania
Antelman G, Spiegelman D, Narh R, Hunter D, Fawzi W, Msamanga G, Urassa E. Nutritional Factors and Infectious Disease Contribute to Anemia among Pregnant Women with Human Immunodeficiency Virus in Tanzania. Journal Of Nutrition 2000, 130: 1950-1957. PMID: 10917907, DOI: 10.1093/jn/130.8.1950.Peer-Reviewed Original ResearchConceptsBody mass indexHuman immunodeficiency virusSevere anemiaImmunodeficiency virusPregnant womenRetinol levelsRisk factorsPositive pregnant womenMean hemoglobin levelSerum retinol levelsMalaria parasite densitySignificant risk factorsPublic health recommendationsCross-sectional studySignificant independent associationAdverse nutritional consequencesHealth education messagesHIV infectionHemoglobin levelsMass indexVitamin supplementationEarly pregnancyIron supplementationIndependent associationClinical trialsVitamin A supplementation and other predictors of anemia among children from Dar Es Salaam, Tanzania.
Villamor E, Mbise R, Spiegelman D, Ndossi G, Fawzi WW. Vitamin A supplementation and other predictors of anemia among children from Dar Es Salaam, Tanzania. American Journal Of Tropical Medicine And Hygiene 2000, 62: 590-7. PMID: 11289670, DOI: 10.4269/ajtmh.2000.62.590.Peer-Reviewed Original ResearchConceptsSevere anemiaHemoglobin levelsHuman immunodeficiency virus (HIV) infectionPredictors of anemiaPlacebo-controlled trialImmunodeficiency virus infectionMean hemoglobin levelAssociation of hemoglobinMonths of breastfeedingDiagnosis of malariaYears of agePotential confounding variablesMonth old infantsLow socioeconomic statusHIV infectionIndependent determinantsMalaria infectionMaternal levelsAdditional dosesNonsignificant reductionHematologic profileVirus infectionSignificant fallHemoglobin concentrationVitamin A