2001
Plasma leptin concentrations and four-year weight gain among US men
Chu N, Spiegelman D, Yu J, Rifai N, Hotamisligil G, Rimm E. Plasma leptin concentrations and four-year weight gain among US men. International Journal Of Obesity 2001, 25: 346-353. PMID: 11319631, DOI: 10.1038/sj.ijo.0801549.Peer-Reviewed Original ResearchConceptsPlasma leptin concentrationsBaseline body mass indexPlasma leptin levelsLeptin levelsSubsequent weight gainLeptin concentrationsWeight gainInsulin levelsLeptin resistanceUS menSoluble tumor necrosis factor receptor levelsTumor necrosis factor receptor levelsBaseline plasma leptin levelsElevated plasma leptin concentrationsFour-year prospective studyDetailed lifestyle questionnaireHigher baseline leptinHealth Professionals FollowBody mass indexTotal energy intakeBody fat massPlasma insulin levelsDevelopment of obesityFollow-up questionnaireBaseline leptin
2000
Glycemic status and soluble tumor necrosis factor receptor levels in relation to plasma leptin concentrations among normal weight and overweight US men
Chu N, Spiegelman D, Rifai N, Hotamisligil G, Rimm E. Glycemic status and soluble tumor necrosis factor receptor levels in relation to plasma leptin concentrations among normal weight and overweight US men. International Journal Of Obesity 2000, 24: 1085-1092. PMID: 11033975, DOI: 10.1038/sj.ijo.0801361.Peer-Reviewed Original ResearchConceptsPlasma leptinSTNF-R1C-peptideOverweight menGlycemic statusLeptin concentrationsGlucose homeostasisSoluble tumor necrosis factor receptor levelsSoluble tumour necrosis factor receptor concentrationsTumor necrosis factor receptor levelsDetailed lifestyle questionnaireSTNF-R2 concentrationsHealth Professionals FollowBody mass indexPlasma leptin levelsObesity-related disordersAdipose-derived cytokineCross-sectional studyConsiderable inter-individual variationProfessionals FollowDiabetes mellitusLeptin levelsMass indexNormal weightHighest quintile