2005
Selenium status, pregnancy outcomes, and mother-to-child transmission of HIV-1.
Kupka R, Garland M, Msamanga G, Spiegelman D, Hunter D, Fawzi W. Selenium status, pregnancy outcomes, and mother-to-child transmission of HIV-1. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2005, 39: 203-10. PMID: 15905738.Peer-Reviewed Original ResearchConceptsPregnancy outcomesPregnant womenChild transmissionLow selenium statusHIV transmissionMaternal HIV disease progressionHIV-positive pregnant womenSelenium statusDirect epidemiologic evidenceMTCT of HIVLow plasma selenium levelsHIV disease progressionPoor pregnancy outcomesRisk of motherWeeks of gestationMother-child pairsPlasma selenium levelsAdequate selenium statusFetal deathGestational ageEpidemiologic evidenceLow birthweightDisease progressionGenital tractHIV-1
2004
Selenium Status Is Associated with Accelerated HIV Disease Progression among HIV-1–Infected Pregnant Women in Tanzania
Kupka R, Msamanga GI, Spiegelman D, Morris S, Mugusi F, Hunter DJ, Fawzi WW. Selenium Status Is Associated with Accelerated HIV Disease Progression among HIV-1–Infected Pregnant Women in Tanzania. Journal Of Nutrition 2004, 134: 2556-2560. PMID: 15465747, DOI: 10.1093/jn/134.10.2556.Peer-Reviewed Original ResearchConceptsPlasma selenium levelsCD4 cell countRisk of mortalityDisease progressionHIV-1-infected pregnant womenCell countSelenium levelsLow plasma selenium levelsHIV disease progressionAccelerated disease progressionCox multivariate modelSelenium statusMedian followHIV diseaseClinical outcomesPregnant womenPoor survivalTanzanian womenMultivariate modelL increaseCells/ProgressionWomenMortalityFirst year