Evaluation of ER/PR and HER2 status by RNA sequencing in tissue core biopsies from preoperative clinical trial specimens.
Kamalakaran S, Lezon-Geyda K, Varadan V, Banerjee N, Lannin D, Rizack T, Sikov W, Abu-Khalaf M, Janevski A, Harris L. Evaluation of ER/PR and HER2 status by RNA sequencing in tissue core biopsies from preoperative clinical trial specimens. Journal Of Clinical Oncology 2011, 29: 46-46. DOI: 10.1200/jco.2011.29.27_suppl.46.Peer-Reviewed Original ResearchER/PRVe tumoursCore biopsyHER2 statusER-ve tumoursPreoperative clinical trialHER2 IHC 2Breast core biopsyTissue core biopsyFresh frozen biopsiesPAM50 analysisNab-paclitaxelER statusClinical statusIHC 2Clinical trialsMolecular subtypesPatient tumorsBreast cancer transcriptomeClinical utilityTherapy trialsTumorsMolecular subtypingBiopsyPAM50 classification