Multicenter Trial of Sentinel Node Biopsy for Breast Cancer Using Both Technetium Sulfur Colloid and Isosulfan Blue Dye
Tafra L, Lannin D, Swanson M, Van Eyk J, Verbanac K, Chua A, Ng P, Edwards M, Halliday B, Henry C, Sommers L, Carman C, Molin M, Yurko J, Perry R, Williams A. Multicenter Trial of Sentinel Node Biopsy for Breast Cancer Using Both Technetium Sulfur Colloid and Isosulfan Blue Dye. Annals Of Surgery 2001, 233: 51-59. PMID: 11141225, PMCID: PMC1421166, DOI: 10.1097/00000658-200101000-00009.Peer-Reviewed Original ResearchConceptsSentinel node biopsyMulticenter trialTechnetium sulfur colloidNode biopsyIsosulfan blueFalse negative rateOlder patientsSulfur colloidBreast cancerComplete lymph node dissectionInexperienced surgeonsLymph node dissectionMetastatic axillary nodesIsosulfan blue dyeSingle-institution seriesSentinel node localizationBreast cancer metastasisAnalysis of tumorsFalse-negative resultsNode dissectionAxillary nodesIndependent predictorsSentinel nodesPoor success ratePatients