Targeted intracellular delivery of dimeric STINGa by two pHLIP peptides for treatment of solid tumors
Moshnikova A, DuPont M, Iraca M, Klumpp C, Visca H, Allababidi D, Pelzer P, Engelman D, Andreev O, Reshetnyak Y. Targeted intracellular delivery of dimeric STINGa by two pHLIP peptides for treatment of solid tumors. Frontiers In Pharmacology 2024, 15: 1346756. PMID: 38495104, PMCID: PMC10940318, DOI: 10.3389/fphar.2024.1346756.Peer-Reviewed Original ResearchTargeted intracellular deliveryIntracellular deliveryTreatment of solid tumorsAnti-cancer immunityPHLIP peptideBinding to plasma proteinsBlood half-lifeTumor eradicationSolid tumorsCytokine activityTumorTargeted deliveryDelivery approachesHalf-lifePlasma proteinsDMSAPHLIPDeliveryMembrane lipid bilayerPeptide