Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning
Shetty R, Joshi D, Jain M, Vasudevan M, Paul J, Bhat G, Banerjee P, Abe T, Kiyonari H, VijayRaghavan K, Inamdar M. Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning. Scientific Reports 2018, 8: 5632. PMID: 29618843, PMCID: PMC5884795, DOI: 10.1038/s41598-018-24014-w.Peer-Reviewed Original ResearchConceptsMouse developmentGenome-wide transcriptome analysisFirst knockout mouseDirectional cell migrationExtracellular matrix organizationExtra-embryonic tissuesSpheroid sprouting assaysEmbryonic day 9.5Endothelial cellsCKO embryosCardiovascular patterningNull embryosTranscriptome analysisRudhiraVascular patterningCardiovascular developmentCytoskeletal proteinsMolecular processesMatrix organizationCell adhesionCell migrationDay 9.5Peptidase activityYolk sacEssential role