2020
De novo damaging variants associated with congenital heart diseases contribute to the connectome
Ji W, Ferdman D, Copel J, Scheinost D, Shabanova V, Brueckner M, Khokha MK, Ment LR. De novo damaging variants associated with congenital heart diseases contribute to the connectome. Scientific Reports 2020, 10: 7046. PMID: 32341405, PMCID: PMC7184603, DOI: 10.1038/s41598-020-63928-2.Peer-Reviewed Original ResearchMeSH KeywordsConnectomeDNA HelicasesDNA-Binding ProteinsExomeFemaleHeart Defects, CongenitalHistone-Lysine N-MethyltransferaseHomeodomain ProteinsHumansMaleMi-2 Nucleosome Remodeling and Deacetylase ComplexMutationMutation, MissenseMyeloid-Lymphoid Leukemia ProteinNerve Tissue ProteinsProtein Tyrosine Phosphatase, Non-Receptor Type 11Receptor, Notch1ConceptsDe novo variantsNDD genesCardiac patterningDe novo damaging variantsDamaging de novo variantsCHD genesDamaging variantsGenesProtein truncatingGenetic originNovo variantsGene mutationsPatterningRecent studiesDendritic developmentVariantsMutationsNeurogenesisSynaptogenesisBonferroni correction
2015
A Smartphone Application to Diagnose the Mechanism of Pediatric Supraventricular Tachycardia
Ferdman DJ, Liberman L, Silver ES. A Smartphone Application to Diagnose the Mechanism of Pediatric Supraventricular Tachycardia. Pediatric Cardiology 2015, 36: 1452-1457. PMID: 25958154, DOI: 10.1007/s00246-015-1185-6.Peer-Reviewed Original ResearchConceptsAtrioventricular nodal reentrant tachycardiaAtrioventricular reentrant tachycardiaSupraventricular tachycardiaPediatric patientsReentrant tachycardiaHolter monitorNodal reentrant tachycardiaPediatric supraventricular tachycardiaChi-square testSingle-lead ECGPediatric electrophysiologistsProspective studyRetrograde P wavesSVT mechanismTachycardia mechanismCorrect diagnosisPatientsPairs of sinusesTachycardiaSmartphone applicationECG
2014
Subcutaneous Treprostinil for Pulmonary Hypertension in Chronic Lung Disease of Infancy
Ferdman DJ, Rosenzweig EB, Zuckerman WA, Krishnan U. Subcutaneous Treprostinil for Pulmonary Hypertension in Chronic Lung Disease of Infancy. Pediatrics 2014, 134: e274-e278. PMID: 24982101, DOI: 10.1542/peds.2013-2330.Peer-Reviewed Original ResearchConceptsPulmonary arterial hypertensionChronic lung diseaseSevere pulmonary arterial hypertensionFormer premature infantsSubcutaneous treprostinilLung diseaseArterial hypertensionPulmonary hypertensionPremature infantsPersistent pulmonary arterial hypertensionIntravenous prostanoid therapySimilar hemodynamic effectsStandard respiratory careTargeted PAH therapyWeeks of therapyCatheter-related complicationsRight ventricular functionCentral venous accessSubgroup of patientsLife-threatening diseasePAH therapyProstanoid therapyConservative therapyHemodynamic effectsPreterm infants
2011
Common Atrium and Pulmonary Vascular Disease
Ferdman DJ, Brady D, Rosenzweig EB. Common Atrium and Pulmonary Vascular Disease. Pediatric Cardiology 2011, 32: 595-598. PMID: 21344289, DOI: 10.1007/s00246-011-9919-6.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsBiopsyCardiac CatheterizationChildChild, PreschoolEchocardiographyFemaleFollow-Up StudiesHeart AtriaHeart Defects, CongenitalHeart Septal Defects, AtrialHeart Septal Defects, VentricularHumansHypertension, PulmonaryInfantMalePulmonary ArteryVascular ResistanceYoung AdultConceptsPulmonary vascular diseaseVascular diseaseCommon atriumEarly pulmonary vascular diseaseSevere pulmonary vascular diseaseLarge atrial septal defectPulmonary hypertension therapyUnderwent surgical repairAtrial septal defectClinical courseSurgical repairCase seriesHypertension therapySeptal defectSurgical correctionPatientsDiseaseAtriumAge 2Early monitoringFirst yearTherapy