2000
Domain-specific recruitment of amide amino acids for protein synthesis
Tumbula D, Becker H, Chang W, Söll D. Domain-specific recruitment of amide amino acids for protein synthesis. Nature 2000, 407: 106-110. PMID: 10993083, DOI: 10.1038/35024120.Peer-Reviewed Original ResearchConceptsGlutaminyl-tRNA synthetaseAsparaginyl-tRNA synthetaseProtein synthesisAmino acidsAminoacyl-transfer RNAAmino acid metabolismGlu-tRNAGlnAsn-tRNAProtein biosynthesisGln-tRNAArchaeaTRNASynthetaseAmidotransferaseBacteriaAmidotransferasesDirect evidenceDifferent mechanismsBiosynthesisCentral importanceCrucial stepRNAOrganismsDomainCytoplasm
1971
Purification of an Escherichia coli Leucine Suppressor Transfer Ribonucleic Acid and Its Aminoacylation by the Homologous Leucyl-Transfer Ribonucleic Acid Synthetase
Hayashi H, Söll D. Purification of an Escherichia coli Leucine Suppressor Transfer Ribonucleic Acid and Its Aminoacylation by the Homologous Leucyl-Transfer Ribonucleic Acid Synthetase. Journal Of Biological Chemistry 1971, 246: 4951-4954. PMID: 4941862, DOI: 10.1016/s0021-9258(18)61955-6.Peer-Reviewed Original ResearchMeSH KeywordsAcylationBenzoatesBiological AssayCarbon IsotopesChromatography, DEAE-CelluloseColiphagesEscherichia coliGenetics, MicrobialKineticsLeucineLigasesMutationPeptide BiosynthesisPlant Growth RegulatorsPlants, ToxicPolynucleotidesRNA, TransferSuppression, GeneticTemplates, GeneticTobaccoValineEnzymatic Modification of Transfer RNA
Söll D. Enzymatic Modification of Transfer RNA. Science 1971, 173: 293-299. PMID: 4934576, DOI: 10.1126/science.173.3994.293.Peer-Reviewed Original ResearchConceptsTRNA-modifying enzymesTRNA moleculesTRNA genesTransfer RNAAmino acid biosynthesisParticular tRNA speciesNucleic acid-protein interactionsAminoacyl-tRNA synthetaseSimple selection procedureAmino acid acceptorPrecursor tRNAsActive tRNAMature tRNACellular processesTRNA speciesRegulatory mutantsAcid biosynthesisRNA precursorsProtein factorsIsoacceptor tRNAsDifferent amino acidsNucleotide sequencePolynucleotide levelBiological functionsTRNA
1969
Transfer ribonucleic acid from Mycoplasma.
Hayashi H, Fisher H, Soell D. Transfer ribonucleic acid from Mycoplasma. Biochemistry 1969, 8: 3680-6. PMID: 4897946, DOI: 10.1021/bi00837a028.Peer-Reviewed Original ResearchAmino AcidsCarbon IsotopesCell-Free SystemCelluloseChemical PhenomenaChemistryChromatography, Ion ExchangeChromatography, PaperElectrophoresisEscherichia coliFormatesHot TemperatureMethionineMycoplasmaNucleic Acid DenaturationNucleosidesPeptide BiosynthesisPolynucleotidesRNA, BacterialRNA, TransferSpecies SpecificityStimulation, ChemicalTritiumUltracentrifugationUracil NucleotidesMechanism of protein biosynthesis.
Lengyel P, Söll D. Mechanism of protein biosynthesis. Microbiology And Molecular Biology Reviews 1969, 33: 264-301. PMID: 4896351, PMCID: PMC378322, DOI: 10.1128/br.33.2.264-301.1969.Peer-Reviewed Original Research
1968
Structure and function of Escherichia coli ribosomes II. Translational fidelity and efficiency in protein synthesis of a protein-deficient subribosomal particle
Traub P, Söll D, Nomura M. Structure and function of Escherichia coli ribosomes II. Translational fidelity and efficiency in protein synthesis of a protein-deficient subribosomal particle. Journal Of Molecular Biology 1968, 34: 595-608. PMID: 4938559, DOI: 10.1016/0022-2836(68)90183-6.Peer-Reviewed Original ResearchBiosynthesis of the Peptidoglycan of Bacterial Cell Walls X. Further Study of the Glycyl Transfer Ribonucleic Acids Active in Peptidoglycan Synthesis in Staphylococcus Aureus
Bumsted R, Dahl J, Söll D, Strominger J. Biosynthesis of the Peptidoglycan of Bacterial Cell Walls X. Further Study of the Glycyl Transfer Ribonucleic Acids Active in Peptidoglycan Synthesis in Staphylococcus Aureus. Journal Of Biological Chemistry 1968, 243: 779-782. PMID: 4867040, DOI: 10.1016/s0021-9258(19)81733-7.Peer-Reviewed Original ResearchBiosynthesis of the Peptidoglycan of Bacterial Cell Walls VI. Incorporation Of l-Threonine Into Interpeptide Bridges in Micrococcus Roseus
Roberts W, Strominger J, Söll D. Biosynthesis of the Peptidoglycan of Bacterial Cell Walls VI. Incorporation Of l-Threonine Into Interpeptide Bridges in Micrococcus Roseus. Journal Of Biological Chemistry 1968, 243: 749-756. PMID: 5638591, DOI: 10.1016/s0021-9258(19)81729-5.Peer-Reviewed Original ResearchBiosynthesis of the Peptidoglycan of Bacterial Cell Walls VII. Incorporation of Serine and Glycine into Interpeptide Bridges in Staphylococcus Epidermidis
Petit J, Strominger J, Söll D. Biosynthesis of the Peptidoglycan of Bacterial Cell Walls VII. Incorporation of Serine and Glycine into Interpeptide Bridges in Staphylococcus Epidermidis. Journal Of Biological Chemistry 1968, 243: 757-767. PMID: 5638592, DOI: 10.1016/s0021-9258(19)81730-1.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholsBacitracinCarbon IsotopesCell WallChloramphenicolChlortetracyclineChromatography, Ion ExchangeCycloserineErythromycinGlycoproteinsLincomycinNovobiocinPenicillinsPeptide BiosynthesisPolysaccharides, BacterialPuromycinRistocetinSerineStaphylococcusStreptomycinSurface-Active AgentsTritiumVancomycinConceptsPeptidoglycan synthesis
1967
Studies on polynucleotides LXVII. Initiation of protein synthesis in vitro as studied by using ribopolynucleotides with repeating nucleotide sequences as messengers
Ghosh H, Söll D, Khorana H. Studies on polynucleotides LXVII. Initiation of protein synthesis in vitro as studied by using ribopolynucleotides with repeating nucleotide sequences as messengers. Journal Of Molecular Biology 1967, 25: 275-298. PMID: 5340533, DOI: 10.1016/0022-2836(67)90142-8.Peer-Reviewed Original Research