1983
Each element of the Drosophila tRNA Arg gene split promoter directs transcription in Xenopus oocytes
Sharp S, Dingermann T, Schaack J, Sharp J, Burke D, DeRobertis E, Söll D. Each element of the Drosophila tRNA Arg gene split promoter directs transcription in Xenopus oocytes. Nucleic Acids Research 1983, 11: 8677-8690. PMID: 6561520, PMCID: PMC326616, DOI: 10.1093/nar/11.24.8677.Peer-Reviewed Original ResearchConceptsD-control regionDrosophila tRNAArg geneTRNAArg geneEukaryotic tRNA gene transcriptionXenopus oocytesRNA polymerase III transcription factorT-control regionEukaryotic tRNA genesTRNA gene transcriptionIntragenic control regionTranscription initiation siteSpecific DNA sequencesTRNA genesTranscription initiationArg genesControl regionTranscription factorsGene transcriptionDNA sequencesMutant formsOocyte nucleusSequence 5Initiation siteGenesTranscription
1980
Dimeric transfer RNA precursors in S. pombe
Mao J, Schmidt O, Söll D. Dimeric transfer RNA precursors in S. pombe. Cell 1980, 21: 509-516. PMID: 7407924, DOI: 10.1016/0092-8674(80)90488-2.Peer-Reviewed Original ResearchConceptsTRNA genesNucleotide intronRNA precursorsDNA fragmentsNuclear extractsNucleotide spacerPrimary transcription productTransfer RNA precursorsNucleotide leader sequenceS. pombeTRNA sequencesTrailer sequencesRNA initiationLeader sequenceTRNA moleculesTranscription productsEnzymatic stepsSequence analysisRNA analysisXenopus oocytesGenesEndonuclease cleavageIntronsTerminusSequenceTwo control regions for eukaryotic tRNA gene transcription.
DeFranco D, Schmidt O, Söll D. Two control regions for eukaryotic tRNA gene transcription. Proceedings Of The National Academy Of Sciences Of The United States Of America 1980, 77: 3365-3368. PMID: 6774336, PMCID: PMC349616, DOI: 10.1073/pnas.77.6.3365.Peer-Reviewed Original ResearchConceptsControl regionTRNALys geneGene transcriptionEukaryotic tRNA gene transcriptionTRNA gene transcriptionInternal control regionIdentical coding sequenceShort leader sequencePrecursor tRNAsTranscription initiationMature tRNALeader sequenceCoding sequencePBR322 sequencesNuclear extractsRecombinant plasmidTranscriptionXenopus oocytesGenesTRNASequence