Inactivation of nonsense suppressor transfer RNA genes in Schizosaccharomyces pombe Intergenic conversion and hot spots of mutation
Heyer W, Münz P, Amstutz H, Aebi R, Gysler C, Schuchert P, Szankasi P, Leupold U, Kohli J, Gamulin V, Söll D. Inactivation of nonsense suppressor transfer RNA genes in Schizosaccharomyces pombe Intergenic conversion and hot spots of mutation. Journal Of Molecular Biology 1986, 188: 343-353. PMID: 3735426, DOI: 10.1016/0022-2836(86)90159-2.Peer-Reviewed Original ResearchConceptsTRNA genesSuppressor tRNA geneIntergenic conversionDNA sequencesTransfer RNA genesYeast Schizosaccharomyces pombeSerine tRNA geneCrosses of strainsSame molecular mechanismsConcerted evolutionRNA genesProgeny sporesSchizosaccharomyces pombeAllelic conversionDifferent chromosomesConversion eventsIntron sequencesSequence transferMolecular mechanismsMutation hot spotsSpontaneous mutationsVegetative cellsGenesPoint mutationsSuppressor activity