1979
Regulation of biosynthesis of aminoacyl-transfer RNA synthetases and of transfer-RNA in Escherichia coli.
Morgan S, Larossa R, Cheung A, Low B, Söll D. Regulation of biosynthesis of aminoacyl-transfer RNA synthetases and of transfer-RNA in Escherichia coli. Biological Research 1979, 12: 415-26. PMID: 45219.Peer-Reviewed Original ResearchConceptsGlutaminyl-tRNA synthetaseLeucyl-tRNA synthetaseGlnR mutantRegulation of biosynthesisClasses of mutantsTemperature-resistant revertantsOperator-promoter regionAminoacyl-transfer RNA synthetasesStructural geneLeu genesRegulatory mutantsThermolabile leucyl-tRNA synthetaseMutantsResistant revertantsFormation of glutamineGlutamine synthetaseE. coli strainsEscherichia coliRNA synthetasesGenesSynthetaseElevated levelsRevertantsColi strainsGlnT
1977
Regulation of biosynthesis of aminoacyl-tRNA synthetases and of tRNA in Escherichia coli I. Isolation and characterization of a mutant with elevated levels of tRNAGln1
Morgan S, Körner A, Low K, Söll D. Regulation of biosynthesis of aminoacyl-tRNA synthetases and of tRNA in Escherichia coli I. Isolation and characterization of a mutant with elevated levels of tRNAGln1. Journal Of Molecular Biology 1977, 117: 1013-1031. PMID: 24122, DOI: 10.1016/s0022-2836(77)80010-7.Peer-Reviewed Original ResearchConceptsGlutaminyl-tRNA synthetaseAminoacyl-tRNA synthetasesRegulation of biosynthesisEscherichia coli strainsGlutamine synthetaseSpontaneous revertantsSynthetasesColi strainsMutantsSynthetaseElevated levelsRevertantsI. IsolationTRNABiosynthesisDuplicationSpeciesMutationsGlnTRegulationOverproductionIsolation