PDE4D And HCN1 Ultrastructure In Rhesus Macaque Entorhinal Cortex: Relevance For Aging And Alzheimer's Disease
Datta D, Mentone S, Arnsten A. PDE4D And HCN1 Ultrastructure In Rhesus Macaque Entorhinal Cortex: Relevance For Aging And Alzheimer's Disease. Innovation In Aging 2021, 5: 638-639. PMCID: PMC8681434, DOI: 10.1093/geroni/igab046.2410.Peer-Reviewed Original ResearchDNA CpG methylationProtein mass spectrometrySomatic mutationsAge-related molecular changesSimilar genetic backgroundEpigenetic regulatorsCpG methylationEpigenetic alterationsWhole-exome sequencingMolecular damageGenetic backgroundDNAmeMolecular changesPostmortem brain samplesBrain samplesAbstract AgingSame brain samplesAlzheimer's diseaseCurrent understandingBiological agingBinding propertiesMutationsMass spectrometryMajor risk factorEpigenetics