PLCβ Is Critical for T-Cell Chemotaxis In Vivo.
Bach T, Chen Q, Jordan M, Choi J, Wu D, Koretzky G, Zigmond S, Abrams C. PLCβ Is Critical for T-Cell Chemotaxis In Vivo. Blood 2004, 104: 2650. DOI: 10.1182/blood.v104.11.2650.2650.Peer-Reviewed Original ResearchT cell migrationT cellsChronic inflammationNeutrophil chemotaxisDense inflammatory infiltrateSecondary lymphoid organsWild-type T cellsType T cellsPeripheral T cellsWild-type miceMonths of ageWild-type lymphocytesT cell chemotaxisCytoplasmic calcium concentrationNull T cellsChemotactic responseKnockout T cellsInflammatory infiltrateRecipient miceLymphoid organsInflammatory responseSkin ulcersQuin-2 AMPlasma cellsT lymphocytes