Pertussis Toxin-sensitive Activation of Phospholipase C by the C5a and fMet-Leu-Phe Receptors*
Jiang H, Kuang Y, Wu Y, Smrcka A, Simon M, Wu D. Pertussis Toxin-sensitive Activation of Phospholipase C by the C5a and fMet-Leu-Phe Receptors*. Journal Of Biological Chemistry 1996, 271: 13430-13434. PMID: 8662841, DOI: 10.1074/jbc.271.23.13430.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntigens, CDCell LineEnzyme ActivationGTP-Binding ProteinsMolecular Sequence DataPertussis ToxinReceptor, Anaphylatoxin C5aReceptors, ComplementReceptors, Formyl PeptideReceptors, ImmunologicReceptors, PeptideSignal TransductionTransfectionType C PhospholipasesVirulence Factors, BordetellaConceptsPLC-beta3PTX-sensitive G proteinsG proteinsFMet-LeuGbetagamma subunitsCOS-7 cellsPhospholipase CPLC-beta2Receptor-mediated PLC activationPTX-sensitive mannerFMLP-mediated activationPertussis toxinPhe receptorCell activationGi proteinsChemoattractant receptorsReceptorsPLC activationC5aBeta2Gq classActivationBeta3Betagamma subunitsSignal transduction pathways