2024
395 Altered hematopoiesis and functional decline of hematopoietic stem cells in cystic fibrosis mice
Braga C, Mancuso R, Thompson E, Oez H, Gudneppannavar R, Zhang P, Huang P, Egan M, Murray T, Krause D, Bruscia E. 395 Altered hematopoiesis and functional decline of hematopoietic stem cells in cystic fibrosis mice. Journal Of Cystic Fibrosis 2024, 23: s207-s208. DOI: 10.1016/s1569-1993(24)01235-9.Peer-Reviewed Original Research
2021
MRTFA: A critical protein in normal and malignant hematopoiesis and beyond
Reed F, Larsuel ST, Mayday MY, Scanlon V, Krause DS. MRTFA: A critical protein in normal and malignant hematopoiesis and beyond. Journal Of Biological Chemistry 2021, 296: 100543. PMID: 33722605, PMCID: PMC8079280, DOI: 10.1016/j.jbc.2021.100543.Peer-Reviewed Original ResearchConceptsMalignant hematopoiesisActin cytoskeleton dynamicsCritical cellular functionsResponse factorSerum response factorTranscription factor ACellular rolesImmediate early genesProtein partnersTranscriptional regulationCytoskeleton dynamicsCellular functionsTranscriptional targetsTranscription factorsCytoskeletal proteinsCritical proteinsMRTFAEarly genesCell typesChromosomal translocationsHematopoietic cellsCell growthFactor AHematopoiesisMuscle cells
2018
Concise Review: Bipotent Megakaryocytic-Erythroid Progenitors: Concepts and Controversies
Xavier-Ferrucio J, Krause DS. Concise Review: Bipotent Megakaryocytic-Erythroid Progenitors: Concepts and Controversies. Stem Cells 2018, 36: 1138-1145. PMID: 29658164, PMCID: PMC6105498, DOI: 10.1002/stem.2834.Peer-Reviewed Original ResearchConceptsMegakaryocytic-erythroid progenitorsProgenitor cellsDifferent functional outputsVariety of speciesProgenitor stageIntermediate progenitor stageErythroid cellsHuman hematopoiesisBlood formationMegakaryocytic lineageMurine cellsHematopoietic stemHematopoietic progenitorsFunctional outputStem cellsDifferentiation capabilityHematopoiesis processProgenitorsLineagesHematopoiesisCell sourceCellsDiscrete stepsRecent advancesSpecies
1998
CD34 expression by embryonic hematopoietic and endothelial cells does not require c-Myb.
Krause DS, Mucenski ML, Lawler AM, May WS. CD34 expression by embryonic hematopoietic and endothelial cells does not require c-Myb. Experimental Hematology 1998, 26: 1086-92. PMID: 9766450.Peer-Reviewed Original ResearchConceptsC-MybDevelopmental hematopoiesisES cellsPromoter activityHematopoietic cellsD3 embryonic stem cellsStage-specific mannerES cell differentiationEmbryonic stem cellsPrimitive hematopoietic cellsDefinitive hematopoiesisBone marrow stemCell surface glycoproteinBlood islandsEmbryoid bodiesEndothelial cellsTransient transfectionCell differentiationEmbryosStem cellsProgenitor cellsYolk sacHematopoiesisNonhematopoietic cellsCD34 expression
1997
Gotta find GATA a friend
Krause D, Perkins A. Gotta find GATA a friend. Nature Medicine 1997, 3: 960-961. PMID: 9288719, DOI: 10.1038/nm0997-960.Commentaries, Editorials and Letters