Immunohistochemical and molecular features of cholangiolocellular carcinoma are similar to well-differentiated intrahepatic cholangiocarcinoma
Balitzer D, Joseph NM, Ferrell L, Shafizadeh N, Jain D, Zhang X, Yeh M, di Tommaso L, Kakar S. Immunohistochemical and molecular features of cholangiolocellular carcinoma are similar to well-differentiated intrahepatic cholangiocarcinoma. Modern Pathology 2019, 32: 1486-1494. PMID: 31186529, DOI: 10.1038/s41379-019-0290-0.Peer-Reviewed Original ResearchConceptsCholangiolocellular carcinomaIntrahepatic cholangiocarcinomaLow-grade cytologic atypiaPrimary liver carcinomaCapture-based next-generation sequencingCanals of HeringNumber alterationsHistologic subtypeCarcinoma componentCytologic atypiaImmunohistochemistry resultsCholangiocarcinomaLiver carcinomaCarcinomaSelect intronsCell subtypesStem cell subtypesHepatocellular componentDistinct entityMutational profileSubtypesNext-generation sequencingCD56Genomic profilesCD117