2007
Investigation of potential gene–gene interactions between apoe and reln contributing to autism risk
Ashley-Koch A, Jaworski J, Ma D, Mei H, Ritchie M, Skaar D, Delong G, Worley G, Abramson R, Wright H, Cuccaro M, Gilbert J, Martin E, Pericak-Vance M. Investigation of potential gene–gene interactions between apoe and reln contributing to autism risk. Psychiatric Genetics 2007, 17: 221-226. PMID: 17621165, DOI: 10.1097/ypg.0b013e32809c2f75.Peer-Reviewed Original ResearchApolipoproteins EAutistic DisorderCell Adhesion Molecules, NeuronalElectron Spin Resonance SpectroscopyExtracellular Matrix ProteinsFamilyFemaleGenetic Predisposition to DiseaseHumansMaleNerve Tissue ProteinsPolymorphism, GeneticPolymorphism, Single NucleotideReelin ProteinRisk AssessmentSerine EndopeptidasesUnited StatesWhite People
2005
Identification of Significant Association and Gene-Gene Interaction of GABA Receptor Subunit Genes in Autism
Ma D, Whitehead P, Menold M, Martin E, Ashley-Koch A, Mei H, Ritchie M, DeLong G, Abramson R, Wright H, Cuccaro M, Hussman J, Gilbert J, Pericak-Vance M. Identification of Significant Association and Gene-Gene Interaction of GABA Receptor Subunit Genes in Autism. American Journal Of Human Genetics 2005, 77: 377-388. PMID: 16080114, PMCID: PMC1226204, DOI: 10.1086/433195.Peer-Reviewed Original ResearchConceptsGABA receptor subunit genesReceptor subunit genesSingle nucleotide polymorphismsGene-gene interactionsSubunit geneFamily-based association testAssociation analysisComplex gene-gene interactionsGenotype-pedigree disequilibrium testGenotypic associationDisequilibrium testSignificant genetic componentChromosome 4p12Pedigree disequilibrium testMultiple genesEpigenetic effectsSignificant genotypic associationTwo-locus modelSignificant allelic associationAllelic association analysisGenesGenetic componentLinkage testsMarker setGABRB1