Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci
Hedges D, Hamilton-Nelson K, Sacharow S, Nations L, Beecham G, Kozhekbaeva Z, Butler B, Cukier H, Whitehead P, Ma D, Jaworski J, Nathanson L, Lee J, Hauser S, Oksenberg J, Cuccaro M, Haines J, Gilbert J, Pericak-Vance M. Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci. Molecular Autism 2012, 3: 2. PMID: 22472195, PMCID: PMC3352055, DOI: 10.1186/2040-2392-3-2.Peer-Reviewed Original ResearchGamma-aminobutyric acidGABA receptorsControl individualsGABA receptor expressionMajor inhibitory neurotransmitterCommon insertion/deletion polymorphismInsertion/deletion polymorphismQuantitative PCRGABAergic systemInhibitory neurotransmitterReceptor expressionUnaffected family membersBehavioral impairmentsEtiology of autismAutistic patientsComparative genomic hybridization arrayBackgroundAutism spectrum disorderConclusionsThese results