2024
Preclinical Evidence of the Effects of Sweet Flavors: Sweetness Increases Nicotine Intake and Seeking
Bagdas D, Addy N. Preclinical Evidence of the Effects of Sweet Flavors: Sweetness Increases Nicotine Intake and Seeking. Nicotine & Tobacco Research 2024, ntae241. PMID: 39413033, DOI: 10.1093/ntr/ntae241.Peer-Reviewed Original ResearchNicotine use behaviorsNicotine reinforcementNicotine intakeSelf-administrationNicotine useFlavor exposureUse behaviorsIntravenous nicotine self-administrationPattern of nicotine intakeSessions of self-administrationNicotine self-administrationIncreased nicotine intakeNicotine-related behaviorsSaccharin-flavored solutionInfluence of early exposureSeeking behaviorNo significant sex differencesSignificant sex differencesImpact of early exposureSaccharin exposureEarly exposureFlavored solutionNicotine addictionSex differencesNicotine
2019
Adolescent but not adult ethanol binge drinking modulates ethanol behavioral effects in mice later in life
Younis R, Wolstenholme J, Bagdas D, Bettinger J, Miles M, Damaj M. Adolescent but not adult ethanol binge drinking modulates ethanol behavioral effects in mice later in life. Pharmacology Biochemistry And Behavior 2019, 184: 172740. PMID: 31326461, PMCID: PMC6697373, DOI: 10.1016/j.pbb.2019.172740.Peer-Reviewed Original ResearchConceptsEthanol intakeEthanol drinkingEthanol's behavioral effectsEarly exposureAdolescent ethanol exposureEnhanced ethanol intakeAlcohol use disorderAnxiety-related behaviorAdolescence altersDrug-taking behaviorAlcohol intakeC57BL/6J miceEthanol exposureWithdrawal stateLong-term effectsNeurochemical mechanismsMouse modelBinge drinkingAdult miceUse disordersSerious illnessAbuse liabilityDrinking paradigmAdult exposureAdolescent population