2016
Divergence and rewiring of regulatory networks for neural development between human and other species
Wang P, Zhao D, Rockowitz S, Zheng D. Divergence and rewiring of regulatory networks for neural development between human and other species. Neurogenesis 2016, 3: e1231495. PMID: 27900343, PMCID: PMC5111580, DOI: 10.1080/23262133.2016.1231495.Peer-Reviewed Original ResearchRegulatory networksTranscription factorsNeural developmentMouse embryonic stem cellsREST-binding sitesGene regulatory networksCritical transcriptional regulatorREST/NRSFEmbryonic stem cellsTranscriptional regulatorsEpigenetic regulationGenomic regionsGenetic controlMammalian speciesFunctional implicationsGenesStem cellsRest regulationsSpeciesBinding eventsFunctional featuresCritical roleRegulationBrain developmentRecent analysis
2013
Efficient utilization of aerobic metabolism helps Tibetan locusts conquer hypoxia
Zhao D, Zhang Z, Cease A, Harrison J, Kang L. Efficient utilization of aerobic metabolism helps Tibetan locusts conquer hypoxia. BMC Genomics 2013, 14: 631. PMID: 24047108, PMCID: PMC3852963, DOI: 10.1186/1471-2164-14-631.Peer-Reviewed Original ResearchConceptsAerobic metabolismBasic metabolic processesExtreme hypoxiaTranscriptional responseHigh-altitude Tibetan PlateauGeographical populationsTCA cycleMigratory locustHypoxia toleranceMetabolic processesLocusta migratoriaHypoxic responseEntry genesLocustPhysiological perspectiveATP contentMetabolismTibetan PlateauInvertebratesInsectsDifferent altitudesGenesSpeciesHypoxiaConclusionsOur results