2013
Efficient utilization of aerobic metabolism helps Tibetan locusts conquer hypoxia
Zhao D, Zhang Z, Cease A, Harrison J, Kang L. Efficient utilization of aerobic metabolism helps Tibetan locusts conquer hypoxia. BMC Genomics 2013, 14: 631. PMID: 24047108, PMCID: PMC3852963, DOI: 10.1186/1471-2164-14-631.Peer-Reviewed Original ResearchConceptsAerobic metabolismBasic metabolic processesExtreme hypoxiaTranscriptional responseHigh-altitude Tibetan PlateauGeographical populationsTCA cycleMigratory locustHypoxia toleranceMetabolic processesLocusta migratoriaHypoxic responseEntry genesLocustPhysiological perspectiveATP contentMetabolismTibetan PlateauInvertebratesInsectsDifferent altitudesGenesSpeciesHypoxiaConclusionsOur results
2012
Genome-wide analysis of transcriptional changes in the thoracic muscle of the migratory locust, Locusta migratoria, exposed to hypobaric hypoxia
Zhao D, Zhang Z, Harrison J, Kang L. Genome-wide analysis of transcriptional changes in the thoracic muscle of the migratory locust, Locusta migratoria, exposed to hypobaric hypoxia. Journal Of Insect Physiology 2012, 58: 1424-1431. PMID: 22985864, DOI: 10.1016/j.jinsphys.2012.08.006.Peer-Reviewed Original ResearchConceptsAnalysis of transcriptional changesHypoxia-inducible factorGenome-wide analysisPentose phosphate pathwayThoracic musclesPhosphate pathwayEndoplasmic reticulumMitochondrial biogenesisTranscriptional changesTranscriptional profilesDysfunctional proteinsTarget genesMitochondrial activityBiological response to hypoxiaMigratory locustLiving organismsResponse to hypoxiaLocusta migratoriaHigh-altitude regionsBiological responsesOxidative stressBiogenesisImpact of hypobaric hypoxiaPentoseInvertebrates