Functional modulation of mitochondrial cytochrome c oxidase underlies adaptation to high-altitude hypoxia in a Tibetan migratory locust
Zhang ZY, Chen B, Zhao DJ, Kang L. Functional modulation of mitochondrial cytochrome c oxidase underlies adaptation to high-altitude hypoxia in a Tibetan migratory locust. Proceedings Of The Royal Society B 2013, 280: 20122758. PMID: 23390104, PMCID: PMC3574369, DOI: 10.1098/rspb.2012.2758.Peer-Reviewed Original ResearchConceptsCytochrome c oxidaseOxidative phosphorylationLocust populationsHypoxia responseMigratory locustHypoxia toleranceC oxidaseMitochondrial cytochrome c oxidaseElectron transport rateElevated catalytic efficiencyHigher hypoxia toleranceCatalytic redox centerHypoxia adaptationCOX activityMitochondrial structureAerobic organismsFlight musclesMitochondrial mechanismsNovel mechanismLocusta migratoriaLocustFunctional modulationPermanent hypoxiaHypoxic treatmentProtein content