2021
Psychiatric comorbidity and order of condition onset among patients seeking treatment for chronic pain and opioid use disorder
Barry DT, Beitel M, Cutter CJ, Fiellin DA, Madden LM, Lipkind N, Bollampally P, Liong C, Schottenfeld RS. Psychiatric comorbidity and order of condition onset among patients seeking treatment for chronic pain and opioid use disorder. Drug And Alcohol Dependence 2021, 221: 108608. PMID: 33667784, PMCID: PMC8026725, DOI: 10.1016/j.drugalcdep.2021.108608.Peer-Reviewed Original ResearchConceptsOpioid use disorderChronic painPsychiatric comorbidityCondition onsetUse disordersNonopioid substance use disordersDSM-IV-TR Axis I DisordersFirst groupComorbid chronic painStructured Clinical InterviewAxis I DisordersAxis II disordersSubstance use disordersDSM-IV personality disordersStandardized training protocolSame time groupsPotential treatment implicationsClinical trialsDoctoral-level providersI disordersMultinomial logistic regressionPrimary drugClinical InterviewPainDiagnostic Interview
2020
A qualitative investigation of addiction counselors' perceptions and experiences implementing an open-access model for treating opioid use disorder
Oberleitner LMS, Madden LM, Muthulingam D, Marcus R, Oberleitner DE, Beitel M, Gaeta M, Tamberelli JF, Barry DT. A qualitative investigation of addiction counselors' perceptions and experiences implementing an open-access model for treating opioid use disorder. Journal Of Substance Use And Addiction Treatment 2020, 121: 108191. PMID: 33357602, PMCID: PMC7770334, DOI: 10.1016/j.jsat.2020.108191.Peer-Reviewed Original ResearchConceptsMethadone maintenance treatmentTreatment programOpioid treatment programsOpioid use disorderMaintenance treatmentTreatment optionsMethadone maintenanceUse disordersProspective patientsIndividual semi-structured interviewsCounselors' perceptionsTreatment organizationsInterdisciplinary teamCliniciansAddiction counselorsSemi-structured interviewsAlexithymia and pain experience among patients using methadone-maintenance therapy
Morie KP, Potenza MN, Beitel M, Oberleitner LM, Roos CR, Yip SW, Oberleitner DE, Gaeta M, Barry DT. Alexithymia and pain experience among patients using methadone-maintenance therapy. Drug And Alcohol Dependence 2020, 218: 108387. PMID: 33168339, PMCID: PMC8103623, DOI: 10.1016/j.drugalcdep.2020.108387.Peer-Reviewed Original ResearchConceptsOpioid use disorderPain interferencePain acceptancePain experienceUse disordersMethadone maintenance therapySubset of patientsMethadone-treated patientsMethadone maintenance treatmentDrug use historyReporting painPain severityImportant intervention targetMaintenance treatmentMore painPain catastrophizingPainPatientsEffect of alexithymiaTreatment targetsDrug useIntervention targetsRole of alexithymiaRegression analysisSelf-report measuresCorrelates of Homelessness Among Patients in Methadone Maintenance Treatment
Gaeta M, Beitel M, Oberleitner LMS, Oberleitner DE, Madden LM, Tamberelli JF, Barry DT. Correlates of Homelessness Among Patients in Methadone Maintenance Treatment. Medical Care 2020, 58: 1030-1034. PMID: 32925463, PMCID: PMC7668351, DOI: 10.1097/mlr.0000000000001414.Peer-Reviewed Original ResearchConceptsOpioid use disorderImportant public health roleLogistic regressionMethadone maintenance treatment programImportant public health issueTreatment-related correlatesCorrelates of homelessnessPercent of patientsMethadone maintenance treatmentFinal logistic regression modelMaintenance treatment programPublic health roleSymptoms of depressionBivariate logistic regressionPublic health issueLogistic regression modelsMaintenance treatmentUse disordersPatientsSignificant independent variablesHealth roleBivariate analysisTreatment programPast monthHigher symptomsCorrelates of sleep quality and excessive daytime sleepiness in people with opioid use disorder receiving methadone treatment
Baldassarri SR, Beitel M, Zinchuk A, Redeker NS, Oberleitner DE, Oberleitner LMS, Carrasco D, Madden LM, Lipkind N, Fiellin DA, Bastian LA, Chen K, Yaggi HK, Barry DT. Correlates of sleep quality and excessive daytime sleepiness in people with opioid use disorder receiving methadone treatment. Sleep And Breathing 2020, 24: 1729-1737. PMID: 32556918, PMCID: PMC7680294, DOI: 10.1007/s11325-020-02123-z.Peer-Reviewed Original ResearchConceptsOpioid use disorderExcessive daytime sleepinessDaytime sleepinessSleep qualityChronic painExcessive daytimeUse disordersConclusionsPoor sleep qualityCurrent chronic painModifiable risk factorsImpaired sleep qualityMultivariable linear regression modelsBody mass indexPoor sleep qualityNon-significant associationMass indexMultivariable analysisPain interferenceRelated comorbiditiesMethadone treatmentClinical correlatesMean PSQIRisk factorsSleep disordersResultsNinety percentAssociations Among Sleep Disturbance, Pain Catastrophizing, and Pain Intensity for Methadone-maintained Patients With Opioid Use Disorder and Chronic Pain
Martinez CP, Edwards KA, Roos CR, Beitel M, Eller A, Barry DT. Associations Among Sleep Disturbance, Pain Catastrophizing, and Pain Intensity for Methadone-maintained Patients With Opioid Use Disorder and Chronic Pain. The Clinical Journal Of Pain 2020, 36: 641-647. PMID: 32482968, PMCID: PMC7725378, DOI: 10.1097/ajp.0000000000000848.Peer-Reviewed Original ResearchConceptsOpioid use disorderMethadone maintenance treatmentChronic painPain intensitySleep disturbancesMMT patientsUse disordersLarge cross-sectional studyGreater pain intensityCo-occurring chronic painCross-sectional studyCross-sectional associationsGreater sleep disturbanceMaintenance treatmentPain catastrophizingPain issuesKey mechanistic pathwaysPainPatientsGreater painIntensity pathwaySignificant mediation effectSelf-report measuresDisordersAssociationTrajectories of Self-Reported Opioid Use Among Patients With HIV Engaged in Care: Results From a National Cohort Study.
Edelman EJ, Li Y, Barry D, Brennan Braden J, Crystal S, Kerns RD, Gaither JR, Gordon KS, Manhapra A, Merlin JS, Moore BA, Oldfield BJ, Park LS, Rentsch CT, Skanderson M, Williams EC, Justice AC, Tate JP, Becker WC, Marshall BDL. Trajectories of Self-Reported Opioid Use Among Patients With HIV Engaged in Care: Results From a National Cohort Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 84: 26-36. PMID: 32267658, PMCID: PMC7147724, DOI: 10.1097/qai.0000000000002310.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCohort StudiesFemaleHIV InfectionsHumansMaleMiddle AgedOpioid-Related DisordersUnited StatesConceptsOpioid useOpioid use trajectoriesCohort studyPain interferenceSelf-reported opioid useVeterans Aging Cohort StudyVeterans Health Administration sitesInfrequent useOpioid use frequencyMarijuana useAging Cohort StudyNational cohort studyEvidence-based treatmentsGroup-based trajectory modelsProspective cohortBaseline factorsIllness severityMultivariable analysisBenzodiazepine medicationVA carePsychoactive medicationsPrescription painkillersPsychiatric symptomsHeroin useMultinomial logistic regression
2019
High-dose prescribed opioids are associated with increased risk of heroin use among United States military veterans.
Banerjee G, Edelman EJ, Barry DT, Crystal S, Gordon KS, Gordon AJ, Gaither JR, Green TC, Kerns RD, Manhapra A, Moore BA, Fiellin DA, Marshall BDL. High-dose prescribed opioids are associated with increased risk of heroin use among United States military veterans. Pain 2019, 160: 2126-2135. PMID: 31145217, PMCID: PMC6699915, DOI: 10.1097/j.pain.0000000000001606.Peer-Reviewed Original ResearchConceptsHigh-dose opioid prescriptionsOpioid prescriptionsHeroin useCohort studyPrior receiptHepatitis C virus (HCV) infection statusLong-term opioid prescriptionsPast-year heroin useVeterans Aging Cohort StudyHigh-dose opioidsOpioid-prescribing patternsProspective cohort studyAging Cohort StudyOpioid use disorderCurrent national guidelinesUnhealthy alcohol useUnited States veteransUnited States military veteransVirus infection statusPosttraumatic stress disorderOpioid receiptPrescribed opioidsPain interferenceCox regressionStates veteransPain catastrophizing and pain acceptance are associated with pain severity and interference among methadone‐maintained patients
Mun CJ, Beitel M, Oberleitner L, Oberleitner DE, Madden LM, Bollampally P, Barry DT. Pain catastrophizing and pain acceptance are associated with pain severity and interference among methadone‐maintained patients. Journal Of Clinical Psychology 2019, 75: 2233-2247. PMID: 31454081, PMCID: PMC7213971, DOI: 10.1002/jclp.22842.Peer-Reviewed Original ResearchConceptsOpioid use disorderMethadone maintenance treatmentPain severityPain acceptanceChronic painPain interferenceMMT patientsUse disordersCo-occurring opioid use disorderMethadone-maintained patientsMethadone doseImportant intervention targetMaintenance treatmentPain catastrophizingPainPsychosocial interventionsPatientsIntervention targetsPrevious weekSeverityEmotional distressImportant targetSelf-report measuresDisordersPresent studyPredictors of timely opioid agonist treatment initiation among veterans with and without HIV
Wyse JJ, Robbins JL, McGinnis KA, Edelman EJ, Gordon AJ, Manhapra A, Fiellin DA, Moore BA, Korthuis PT, Gaither JR, Gordon K, Skanderson M, Barry DT, Crystal S, Justice A, Kraemer KL. Predictors of timely opioid agonist treatment initiation among veterans with and without HIV. Drug And Alcohol Dependence 2019, 198: 70-75. PMID: 30878769, PMCID: PMC6836871, DOI: 10.1016/j.drugalcdep.2019.01.038.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyOpioid use disorderVeterans Aging Cohort StudyOAT initiationUninfected patientsClinical encountersNational observational cohortAging Cohort StudyAfrican American patientsImproved health outcomesAgonist therapyCohort studyObservational cohortTreatment initiationPredictive factorsEffective treatmentAdjusted modelUninfected controlsUse disordersPsychiatric diagnosisPWHClinical practicePatientsHealth outcomesRural residenceUsing nominal group technique to identify barriers, facilitators, and preferences among patients seeking treatment for opioid use disorder: A needs assessment for decision making support
Muthulingam D, Bia J, Madden LM, Farnum SO, Barry DT, Altice FL. Using nominal group technique to identify barriers, facilitators, and preferences among patients seeking treatment for opioid use disorder: A needs assessment for decision making support. Journal Of Substance Use And Addiction Treatment 2019, 100: 18-28. PMID: 30898324, PMCID: PMC6432946, DOI: 10.1016/j.jsat.2019.01.019.Peer-Reviewed Original ResearchConceptsOpioid use disorderNominal group techniquePharmacologic therapyUse disordersSyringe exchange programsIndividual-level barriersEvidence-based interventionsAddiction treatment centersEvidence-based strategiesOUD treatmentPharmacologic treatmentSpecific medicationsTreatment optionsPharmacologic propertiesMedicationsDecision aidPatient considerationsSide effectsTreatment centersOpioid crisisSpecific knowledge gapsGroup techniqueDecision aid developmentTreatmentTherapyElectronic cigarette and tobacco use in individuals entering methadone or buprenorphine treatment
Baldassarri SR, Fiellin DA, Savage ME, Madden LM, Beitel M, Dhingra LK, Fucito L, Camenga D, Bollampally P, Barry DT. Electronic cigarette and tobacco use in individuals entering methadone or buprenorphine treatment. Drug And Alcohol Dependence 2019, 197: 37-41. PMID: 30769264, PMCID: PMC6637405, DOI: 10.1016/j.drugalcdep.2018.12.012.Peer-Reviewed Original ResearchConceptsOpioid use disorderOpioid agonist therapyCurrent cigarette smokingCigarette smokingEC useHigher oddsFormer smokersLower oddsPsychiatric distressPast cigarette smokingElectronic cigarette useAgonist therapyCurrent smokersBuprenorphine treatmentChronic painTobacco useNicotine dependenceUse disordersSmokingCigarette useMultivariate analysisElectronic cigarettesSmokersCigarettesMultivariate model
2018
A randomized clinical trial of the Recovery Line among methadone treatment patients with ongoing illicit drug use
Moore BA, Buono FD, Lloyd DP, Printz DMB, Fiellin DA, Barry DT. A randomized clinical trial of the Recovery Line among methadone treatment patients with ongoing illicit drug use. Journal Of Substance Use And Addiction Treatment 2018, 97: 68-74. PMID: 30577901, PMCID: PMC6310054, DOI: 10.1016/j.jsat.2018.11.011.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognitive Behavioral TherapyCombined Modality TherapyFemaleHumansIllicit DrugsMaleMethadoneMiddle AgedNarcoticsOpiate Substitution TreatmentOutcome and Process Assessment, Health CareSelf ReportSelf-Help GroupsSelf-ManagementSubstance Abuse DetectionSubstance-Related DisordersTelephoneConceptsMethadone treatment patientsIllicit drug useDrug useTreatment patientsUrine screensOngoing illicit drug useDrug abstinencePrevious small trialsClinical efficacy trialsSelf-reported abstinenceRandomized clinical trialsIllicit drugsSubstance use disordersSelf-management systemCognitive behavioral therapyAdjunctive treatmentPrimary outcomeMethadone treatmentSmall trialsClinical trialsEfficacy trialsAbstinence outcomesUse disordersPatient engagementPatientsAn evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain
Barry DT, Beitel M, Cutter CJ, Fiellin DA, Kerns RD, Moore BA, Oberleitner L, Madden LM, Liong C, Ginn J, Schottenfeld RS. An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain. Drug And Alcohol Dependence 2018, 194: 460-467. PMID: 30508769, PMCID: PMC6312460, DOI: 10.1016/j.drugalcdep.2018.10.015.Peer-Reviewed Original ResearchConceptsOpioid use disorderCognitive behavioral therapyChronic painPreliminary efficacyDrug counselingUse disordersImproved pain outcomesProportion of patientsMethadone-maintained patientsNonmedical opioid useEnd of treatmentPrimary study aimPatient satisfaction ratingsManualized cognitive behavioral therapyOpioid usePain outcomesPain interferenceClinical trialsStandard drug counselingPatientsMean sessionSecondary aimStudy aimPainPilot studyDuration of opioid prescriptions predicts incident nonmedical use of prescription opioids among U.S. veterans receiving medical care
Barry DT, Marshall BDL, Becker WC, Gordon AJ, Crystal S, Kerns RD, Gaither JR, Gordon KS, Justice AC, Fiellin DA, Edelman EJ. Duration of opioid prescriptions predicts incident nonmedical use of prescription opioids among U.S. veterans receiving medical care. Drug And Alcohol Dependence 2018, 191: 348-354. PMID: 30176548, PMCID: PMC6596307, DOI: 10.1016/j.drugalcdep.2018.07.008.Peer-Reviewed Original ResearchConceptsPrescription opioid receiptPrescription opioidsMedical careOpioid receiptVeterans Health Administration primary careNonmedical useMultivariable Cox modelInfectious disease clinicProspective cohort studyProportional hazards regressionPrescription opioid medicationsPublic health problemSubstance use disordersMedication-related characteristicsOpioid therapyOpioid medicationsOpioid prescriptionsCohort studyDisease clinicMedian ageHazards regressionEligible participantsPrimary careRisk factorsIncidence rateExperiences of Burnout among Drug Counselors in A Large Opioid Treatment Program: A Qualitative Investigation
Beitel M, Oberleitner L, Muthulingam D, Oberleitner D, Madden LM, Marcus R, Eller A, Bono MH, Barry DT. Experiences of Burnout among Drug Counselors in A Large Opioid Treatment Program: A Qualitative Investigation. Substance Use & Addiction Journal 2018, 39: 211-217. PMID: 29522381, DOI: 10.1080/08897077.2018.1449051.Peer-Reviewed Original ResearchConceptsExperience of burnoutDrug counselorsTreatment programJob-related demandsIndividual semi-structured interviewsWork engagementCounselor burnoutBurnoutCounselor feedbackPhysiological symptomsSemi-structured interviewsCounselorsQualitative investigationParticipantsPossible experienceSystem-level changesCounselor descriptionsExperienceProgram settingsOpioid treatment programsTreatment gapMultidisciplinary teamEngagementProgramTranscribedAn investigation of an open‐access model for scaling up methadone maintenance treatment
Madden LM, Farnum SO, Eggert KF, Quanbeck AR, Freeman RM, Ball SA, Schottenfeld RS, Shi JM, Savage ME, Barry DT. An investigation of an open‐access model for scaling up methadone maintenance treatment. Addiction 2018, 113: 1450-1458. PMID: 29453891, DOI: 10.1111/add.14198.Peer-Reviewed Original ResearchConceptsNon-medical opioid useOpioid use disorderMethadone maintenance treatmentOpioid useMaintenance treatmentTreatment accessUse disordersTreatment modelMethadone maintenance treatment centersMaintenance treatment centersDeleterious effectsMethadone treatmentPatient mortalityTreatment optionsTreatment outcomesTreatment centersProspective patientsRate of retentionPatient censusRapid enrollmentAddiction treatmentApparent deleterious effectsTreatmentMortalityProgrammatic outcomesPsychotherapy With American Indians: An Exploration of Therapist-Rated Techniques in Three Urban Clinics
Beitel M, Myhra LL, Gone JP, Barber JP, Miller A, Rasband A, Cutter CJ, Schottenfeld RS, Barry DT. Psychotherapy With American Indians: An Exploration of Therapist-Rated Techniques in Three Urban Clinics. Psychotherapy 2018, 55: 45-51. PMID: 29565621, DOI: 10.1037/pst0000156.Peer-Reviewed Original Research
2017
Customized Recommendations and Reminder Text Messages for Automated, Computer-Based Treatment During Methadone
Moore BA, Buono FD, Printz DMB, Lloyd DP, Fiellin DA, Cutter CJ, Schottenfeld RS, Barry DT. Customized Recommendations and Reminder Text Messages for Automated, Computer-Based Treatment During Methadone. Experimental And Clinical Psychopharmacology 2017, 25: 485-495. PMID: 29251978, PMCID: PMC5737744, DOI: 10.1037/pha0000149.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyPatient engagementReminder messagesPreliminary efficacy findingsMethadone-maintained patientsSubstance use disordersIllicit drug useRandomized trialsEfficacy findingsMethadone maintenanceUse disordersPatient useDrug useSystem functionBehavioral therapyComputer-based interventionsPatientsShort latencyTotal call timeTrial 2Trial 1Line callsSelf-management systemCall timeTotal contact timeGroup differences in pain interference, psychiatric disorders, and general medical conditions among Hispanics and whites in the U.S. general population
Barry DT, Glenn CP, Hoff RA, Potenza MN. Group differences in pain interference, psychiatric disorders, and general medical conditions among Hispanics and whites in the U.S. general population. Psychiatry Research 2017, 258: 337-343. PMID: 28886905, PMCID: PMC5681386, DOI: 10.1016/j.psychres.2017.08.049.Peer-Reviewed Original ResearchConceptsGeneral medical conditionsSevere pain interferenceModerate pain interferencePain interferenceMedical conditionsPsychiatric disordersCross-sectional retrospective studyNon-Hispanic white adultsLower pain interferenceGroup differencesSpecific psychiatric disordersU.S. general populationNational Epidemiologic SurveyHispanic respondentsEthnic health disparitiesWhite respondentsRetrospective studyMood disordersGeneral populationEpidemiologic SurveyWhite adultsHealth disparitiesDisordersHeart conditionsFurther studies