2024
Nationwide Assessment of Chronic Pain among Hospitalized Individuals with Co-occurring Post Traumatic Stress Disorder and Substance Use Disorder in the United States
Olayinka O, Alemu B, Nkemjika S, Barry D. Nationwide Assessment of Chronic Pain among Hospitalized Individuals with Co-occurring Post Traumatic Stress Disorder and Substance Use Disorder in the United States. Journal Of Dual Diagnosis 2024, ahead-of-print: 1-10. PMID: 38704860, DOI: 10.1080/15504263.2024.2347489.Peer-Reviewed Original ResearchSubstance use disordersIncreased oddsChronic painPosttraumatic stress disorderNational Inpatient SampleIncreased odds of depressionFactors associated with CPIncreased risk of CPAssessment of chronic painOdds of depressionOdds of anxietyIncreased odds of anxietyMental health disordersRisk of CPMultivariate logistic regression modelOdds of insomniaManagement of CPLogistic regression modelsStress disorderAssociated with substance use disordersHospitalized AmericansEvidence-based managementPost-traumatic stress disorderHospital resource usageDecreased oddsStepped Care for Patients to Optimize Whole Recovery (SC-POWR): An Effectiveness Trial Evaluating a Stepped Care Model for Individuals With Opioid Use Disorder and Chronic Pain.
Rossi R, Cutter C, Beitel M, Covelli M, Fiellin D, Kerns R, Vassilieva S, Olabisi D, Barry D. Stepped Care for Patients to Optimize Whole Recovery (SC-POWR): An Effectiveness Trial Evaluating a Stepped Care Model for Individuals With Opioid Use Disorder and Chronic Pain. Substance Use & Addiction Journal 2024, 29767342241245095. PMID: 38606900, DOI: 10.1177/29767342241245095.Peer-Reviewed Original ResearchTreatment-as-usualOpioid use disorderChronic painCognitive behavioral therapyStepped careNonmedical opioid useEffectiveness trialOpioid useAlcohol useSession of exerciseStepped care modelWeekly group sessionsPain-related outcomesStress reductionDecreased pain intensityUse disorderNational Institutes of HealthOpioid use disorder treatmentCare modelInstitutes of HealthAssociated with higher levelsPain intensityPilot study of patientsPain improvementDurability of treatment response
2023
NIH HEAL Common Data Elements (CDE) implementation: NIH HEAL Initiative IDEA-CC
Adams M, Hurley R, Siddons A, Topaloglu U, Wandner L, Adams M, Arnsten J, Bao Y, Barry D, Becker W, Fiellin D, Fox A, Ghiroli M, Hanmer J, Horn B, Hurlocker M, Jalal H, Joseph V, Merlin J, Murray-Krezan C, Pearson M, Rogal S, Starrels J, Bachrach R, Witkiewitz K, Vasquez A. NIH HEAL Common Data Elements (CDE) implementation: NIH HEAL Initiative IDEA-CC. Pain Medicine 2023, 24: 743-749. PMID: 36799548, PMCID: PMC10321760, DOI: 10.1093/pm/pnad018.Peer-Reviewed Original ResearchConceptsClinical trialsClinical Trials NetworkCDE programsChronic painSecondary data analysisPainTrials NetworkDisease statesOpioidData standardsGeographical codingClinical researchHealing initiationData elementsNational InstituteTrialsDisordersFederal investmentInterventionStandard processDisorder researchSurveyed librariesCDELeveraging toolsNetwork alignment
2022
A cohort study examining the relationship among housing status, patient characteristics, and retention among individuals enrolled in low-barrier-to-treatment-access methadone maintenance treatment
Gaeta Gazzola M, Carmichael ID, Madden LM, Dasgupta N, Beitel M, Zheng X, Eggert KF, Farnum SO, Barry DT. A cohort study examining the relationship among housing status, patient characteristics, and retention among individuals enrolled in low-barrier-to-treatment-access methadone maintenance treatment. Journal Of Substance Use And Addiction Treatment 2022, 138: 108753. PMID: 35277307, DOI: 10.1016/j.jsat.2022.108753.Peer-Reviewed Original ResearchConceptsMethadone maintenance treatmentPatient characteristicsChronic painMaintenance treatmentMMT programHousing statusPsychiatric distressCox proportional hazards modelCurrent chronic painPercent of patientsRetrospective chart reviewLog-rank testProportional hazards modelMann-Whitney U testSocial isolationTreatment discontinuationChart reviewCohort studyConsecutive patientsSignificant negative associationHazards modelMeasures of demographicsPatientsSmoking behaviorU testChapter 22 Cognitive behavioral therapy for chronic pain and opioid use disorder
Gazzola M, Beitel M, Cutter C, Barry D. Chapter 22 Cognitive behavioral therapy for chronic pain and opioid use disorder. 2022, 235-246. DOI: 10.1016/b978-0-12-820237-1.00022-3.Peer-Reviewed Original ResearchOpioid use disorderCognitive behavioral therapyChronic painUse disordersBehavioral therapyClinical management challengesComorbid chronic painPain management interventionsChronic medical conditionsCommon clinical problemPoor pain managementNonopioid pharmacotherapyPromising psychotherapyPain managementIllicit opioidsPsychiatric comorbidityOptimal treatmentMedical conditionsPainClinical problemPatientsSubstance useDisordersBiopsychosocial modelTherapy
2021
Primary care and medication management characteristics among patients receiving office-based opioid treatment with buprenorphine
Du CX, Shi J, Tetrault JM, Madden LM, Barry DT. Primary care and medication management characteristics among patients receiving office-based opioid treatment with buprenorphine. Family Practice 2021, 39: 234-240. PMID: 34893825, PMCID: PMC8947790, DOI: 10.1093/fampra/cmab166.Peer-Reviewed Original ResearchConceptsOffice-based opioid treatmentPrimary care providersOpioid use disorderUrine toxicologyOpioid treatmentMore primary care providersOutpatient primary care clinicsChronic pain statusChronic viral hepatitisPrimary care clinicsCommon comorbid conditionsPrimary care characteristicsAddiction treatment settingsHigher median numberEvidence-based treatment modelsOBOT patientsOBOT programOlder patientsPain statusViral hepatitisCommon medicationsRetrospective reviewCare clinicsChronic painComorbid conditionsA Pilot Investigation of Nonpharmacological Pain Management Intervention Groups in Methadone Maintenance Treatment
DiMeola KA, Haynes J, Barone M, Beitel M, Madden LM, Cutter CJ, Raso A, Gaeta M, Zheng X, Barry DT. A Pilot Investigation of Nonpharmacological Pain Management Intervention Groups in Methadone Maintenance Treatment. Journal Of Addiction Medicine 2021, 16: 229-234. PMID: 34145187, PMCID: PMC8678387, DOI: 10.1097/adm.0000000000000877.Peer-Reviewed Original ResearchConceptsMethadone maintenance treatmentCurrent pain intensityPain intensityMaintenance treatmentAcute increaseIntervention groupCurrent chronic painMood statesCognitive behavioral therapyMMT clinicsChronic painAcute improvementAcute reductionAcute changesSpecific mood statesPainExergame interventionGroup attendanceUnvalidated measuresMonday-FridayPilot investigationBonferroni correctionPatientsT-testInterventionSociodemographic and clinical correlates of gabapentin receipt with and without opioids among a national cohort of patients with HIV
Oldfield BJ, Li Y, Vickers-Smith R, Becker WC, Barry DT, Crystal S, Gordon KS, Kerns RD, Rentsch CT, Marshall BDL, Edelman EJ. Sociodemographic and clinical correlates of gabapentin receipt with and without opioids among a national cohort of patients with HIV. AIDS Care 2021, 34: 1053-1063. PMID: 34114904, PMCID: PMC8664891, DOI: 10.1080/09540121.2021.1939851.Peer-Reviewed Original ResearchConceptsOpioid useHigh dosesSelf-reported opioid useVeterans Aging Cohort StudyHigh-dose opioidsMean daily doseAging Cohort StudyHigh-dose benzodiazepinesNational prospective cohortOpioid doseOpioid receiptCohort studyFoot painProspective cohortDaily doseIndependent predictorsChronic painPain interferenceClinical variablesClinical correlatesNational cohortMultinomial logistic regressionPWHLogistic regressionOpioidsPsychiatric comorbidity and order of condition onset among patients seeking treatment for chronic pain and opioid use disorder
Barry DT, Beitel M, Cutter CJ, Fiellin DA, Madden LM, Lipkind N, Bollampally P, Liong C, Schottenfeld RS. Psychiatric comorbidity and order of condition onset among patients seeking treatment for chronic pain and opioid use disorder. Drug And Alcohol Dependence 2021, 221: 108608. PMID: 33667784, PMCID: PMC8026725, DOI: 10.1016/j.drugalcdep.2021.108608.Peer-Reviewed Original ResearchConceptsOpioid use disorderChronic painPsychiatric comorbidityCondition onsetUse disordersNonopioid substance use disordersDSM-IV-TR Axis I DisordersFirst groupComorbid chronic painStructured Clinical InterviewAxis I DisordersAxis II disordersSubstance use disordersDSM-IV personality disordersStandardized training protocolSame time groupsPotential treatment implicationsClinical trialsDoctoral-level providersI disordersMultinomial logistic regressionPrimary drugClinical InterviewPainDiagnostic Interview
2020
Correlates of sleep quality and excessive daytime sleepiness in people with opioid use disorder receiving methadone treatment
Baldassarri SR, Beitel M, Zinchuk A, Redeker NS, Oberleitner DE, Oberleitner LMS, Carrasco D, Madden LM, Lipkind N, Fiellin DA, Bastian LA, Chen K, Yaggi HK, Barry DT. Correlates of sleep quality and excessive daytime sleepiness in people with opioid use disorder receiving methadone treatment. Sleep And Breathing 2020, 24: 1729-1737. PMID: 32556918, PMCID: PMC7680294, DOI: 10.1007/s11325-020-02123-z.Peer-Reviewed Original ResearchConceptsOpioid use disorderExcessive daytime sleepinessDaytime sleepinessSleep qualityChronic painExcessive daytimeUse disordersConclusionsPoor sleep qualityCurrent chronic painModifiable risk factorsImpaired sleep qualityMultivariable linear regression modelsBody mass indexPoor sleep qualityNon-significant associationMass indexMultivariable analysisPain interferenceRelated comorbiditiesMethadone treatmentClinical correlatesMean PSQIRisk factorsSleep disordersResultsNinety percentAssociations Among Sleep Disturbance, Pain Catastrophizing, and Pain Intensity for Methadone-maintained Patients With Opioid Use Disorder and Chronic Pain
Martinez CP, Edwards KA, Roos CR, Beitel M, Eller A, Barry DT. Associations Among Sleep Disturbance, Pain Catastrophizing, and Pain Intensity for Methadone-maintained Patients With Opioid Use Disorder and Chronic Pain. The Clinical Journal Of Pain 2020, 36: 641-647. PMID: 32482968, PMCID: PMC7725378, DOI: 10.1097/ajp.0000000000000848.Peer-Reviewed Original ResearchConceptsOpioid use disorderMethadone maintenance treatmentChronic painPain intensitySleep disturbancesMMT patientsUse disordersLarge cross-sectional studyGreater pain intensityCo-occurring chronic painCross-sectional studyCross-sectional associationsGreater sleep disturbanceMaintenance treatmentPain catastrophizingPain issuesKey mechanistic pathwaysPainPatientsGreater painIntensity pathwaySignificant mediation effectSelf-report measuresDisordersAssociation
2019
Pain catastrophizing and pain acceptance are associated with pain severity and interference among methadone‐maintained patients
Mun CJ, Beitel M, Oberleitner L, Oberleitner DE, Madden LM, Bollampally P, Barry DT. Pain catastrophizing and pain acceptance are associated with pain severity and interference among methadone‐maintained patients. Journal Of Clinical Psychology 2019, 75: 2233-2247. PMID: 31454081, PMCID: PMC7213971, DOI: 10.1002/jclp.22842.Peer-Reviewed Original ResearchConceptsOpioid use disorderMethadone maintenance treatmentPain severityPain acceptanceChronic painPain interferenceMMT patientsUse disordersCo-occurring opioid use disorderMethadone-maintained patientsMethadone doseImportant intervention targetMaintenance treatmentPain catastrophizingPainPsychosocial interventionsPatientsIntervention targetsPrevious weekSeverityEmotional distressImportant targetSelf-report measuresDisordersPresent study(295) Potential Targets for Pain Management among Patients with Co-Occurring Opioid Use Disorder and Chronic Pain
Mun C, Beitel M, Barry D. (295) Potential Targets for Pain Management among Patients with Co-Occurring Opioid Use Disorder and Chronic Pain. Journal Of Pain 2019, 20: s48. DOI: 10.1016/j.jpain.2019.01.452.Peer-Reviewed Original ResearchOpioid use disorderCo-occurring chronic painChronic painMethadone maintenance treatmentPain interferencePain acceptanceMMT patientsPain severityUse disordersCo-occurring opioid use disordersMethadone dosePain managementPain outcomesPain interventionsRegression modelsMaintenance treatmentPain catastrophizingPainPatientsClinical settingOutcome domainsIntervention targetsAnxiety symptomsPotential targetSignificant predictorsElectronic cigarette and tobacco use in individuals entering methadone or buprenorphine treatment
Baldassarri SR, Fiellin DA, Savage ME, Madden LM, Beitel M, Dhingra LK, Fucito L, Camenga D, Bollampally P, Barry DT. Electronic cigarette and tobacco use in individuals entering methadone or buprenorphine treatment. Drug And Alcohol Dependence 2019, 197: 37-41. PMID: 30769264, PMCID: PMC6637405, DOI: 10.1016/j.drugalcdep.2018.12.012.Peer-Reviewed Original ResearchConceptsOpioid use disorderOpioid agonist therapyCurrent cigarette smokingCigarette smokingEC useHigher oddsFormer smokersLower oddsPsychiatric distressPast cigarette smokingElectronic cigarette useAgonist therapyCurrent smokersBuprenorphine treatmentChronic painTobacco useNicotine dependenceUse disordersSmokingCigarette useMultivariate analysisElectronic cigarettesSmokersCigarettesMultivariate model
2018
An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain
Barry DT, Beitel M, Cutter CJ, Fiellin DA, Kerns RD, Moore BA, Oberleitner L, Madden LM, Liong C, Ginn J, Schottenfeld RS. An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain. Drug And Alcohol Dependence 2018, 194: 460-467. PMID: 30508769, PMCID: PMC6312460, DOI: 10.1016/j.drugalcdep.2018.10.015.Peer-Reviewed Original ResearchConceptsOpioid use disorderCognitive behavioral therapyChronic painPreliminary efficacyDrug counselingUse disordersImproved pain outcomesProportion of patientsMethadone-maintained patientsNonmedical opioid useEnd of treatmentPrimary study aimPatient satisfaction ratingsManualized cognitive behavioral therapyOpioid usePain outcomesPain interferenceClinical trialsStandard drug counselingPatientsMean sessionSecondary aimStudy aimPainPilot studyTraining Addiction Counselors to Deliver a Brief Psychoeducational Intervention for Chronic Pain among Patients in Opioid Agonist Treatment: A Pilot Investigation
Butner JL, Bone C, Martinez C, Kwon G, Beitel M, Madden LM, Bono MH, Eller A, Barry DT. Training Addiction Counselors to Deliver a Brief Psychoeducational Intervention for Chronic Pain among Patients in Opioid Agonist Treatment: A Pilot Investigation. Substance Abuse 2018, 39: 199-205. PMID: 29522379, DOI: 10.1080/08897077.2018.1449052.Peer-Reviewed Original ResearchConceptsPsychosocial interventionsBrief psychosocial interventionAddiction counselorsBrief psychoeducational interventionChronic painRole of counselorsAbsence of trainingPerceived AbilityAppropriate treatment interventionsCounselor's abilityPsychoeducational interventionTreatment counselorsDrug counselorsPositive attitudesTreatment interventionsCounselorsFuture researchKnowledge scorePilot investigationTrainingPre-test knowledge scoreOpioid agonist treatmentAppropriate interventionsInterventionAttitudes
2017
Drug Counselor Responses to Patients’ Pain Reports: A Qualitative Investigation of Barriers and Facilitators to Treating Patients with Chronic Pain in Methadone Maintenance Treatment
Beitel M, Oberleitner L, Kahn M, Kerns RD, Liong C, Madden LM, Ginn J, Barry DT. Drug Counselor Responses to Patients’ Pain Reports: A Qualitative Investigation of Barriers and Facilitators to Treating Patients with Chronic Pain in Methadone Maintenance Treatment. Pain Medicine 2017, 18: 2152-2161. PMID: 28177509, DOI: 10.1093/pm/pnw327.Peer-Reviewed Original ResearchConceptsOpioid use disorderMethadone maintenance treatmentChronic painDrug counselorsMaintenance treatmentTreatment needsUse disordersMedical providersCo-occurring chronic painMethadone maintenance treatment programPain management referralsChronic noncancer painPatient-related barriersMethadone-maintained patientsTreatment of patientsMaintenance treatment programPatients' treatment needsNoncancer painMedication regimensPain managementManagement referralsTreatment adherencePatient improvementPatient reportsPain
2016
Psychiatric Disorders Among Patients Seeking Treatment for Co-Occurring Chronic Pain and Opioid Use Disorder.
Barry DT, Cutter CJ, Beitel M, Kerns RD, Liong C, Schottenfeld RS. Psychiatric Disorders Among Patients Seeking Treatment for Co-Occurring Chronic Pain and Opioid Use Disorder. The Journal Of Clinical Psychiatry 2016, 77: 1413-1419. PMID: 27574837, PMCID: PMC6296217, DOI: 10.4088/jcp.15m09963.Peer-Reviewed Original ResearchConceptsOpioid use disorderCo-occurring chronic painChronic painAxis I DisordersUse disordersPsychiatric disordersI disordersMood disordersCo-occurring opioid use disorderBuprenorphine/naloxone treatmentNonopioid substance use disordersDSM-IV-TR Axis I DisordersCo-occurring psychiatric disordersAnxiety disordersMajority of patientsPersonality disorderMethadone maintenance treatmentTreatment of patientsComorbid psychiatric disordersLifetime mood disordersMajor depressive disorderStructured Clinical InterviewLifetime anxiety disorderSubstance use disordersTreatment Research ProgramPhysical activity, psychiatric distress, and interest in exercise group participation among individuals seeking methadone maintenance treatment with and without chronic pain
Beitel M, Stults-Kolehmainen M, Cutter CJ, Schottenfeld RS, Eggert K, Madden LM, Kerns RD, Liong C, Ginn J, Barry DT. Physical activity, psychiatric distress, and interest in exercise group participation among individuals seeking methadone maintenance treatment with and without chronic pain. American Journal On Addictions 2016, 25: 125-131. PMID: 26824197, DOI: 10.1111/ajad.12336.Peer-Reviewed Original ResearchConceptsMethadone maintenance treatmentPhysical activity levelsExercise group participationChronic painPhysical activityPsychiatric distressMaintenance treatmentActivity levelsPast weekVigorous-intensity physical activityExercise of patientsIntensity physical activityExercise groupExercise interventionPainBrief self-report instrumentPatientsLow levelsSelf-report instrumentDistressWeeksDepressionTreatmentGroup participationParticipantsDrug Counselors’ Attitudes Toward Nonpharmacologic Treatments for Chronic Pain
Oberleitner LM, Beitel M, Schottenfeld RS, Kerns RD, Doucette C, Napoleone R, Liong C, Barry DT. Drug Counselors’ Attitudes Toward Nonpharmacologic Treatments for Chronic Pain. Journal Of Addiction Medicine 2016, 10: 34-39. PMID: 26690289, PMCID: PMC4733570, DOI: 10.1097/adm.0000000000000177.Peer-Reviewed Original ResearchConceptsChronic painNonpharmacologic treatmentsDrug counselorsNonpharmacologic pain treatmentsMethadone-maintained patientsInterdisciplinary pain managementMethadone maintenance treatmentVulnerable patient populationCognitive behavioral therapyNonpharmacologic interventionsPain managementPain treatmentPain interventionsMaintenance treatmentPatient populationPainPatientsHerbal medicineGroup interventionEfficacyInterventionTreatmentPerceived EfficacyTherapyUndertreatment