2019
Genetic Markers of Benzimidazole Resistance among Human Hookworms (Necator americanus) in Kintampo North Municipality, Ghana.
Orr AR, Quagraine JE, Suwondo P, George S, Harrison LM, Dornas FP, Evans B, Caccone A, Humphries D, Wilson MD, Cappello M. Genetic Markers of Benzimidazole Resistance among Human Hookworms (Necator americanus) in Kintampo North Municipality, Ghana. American Journal Of Tropical Medicine And Hygiene 2019, 100: 351-356. PMID: 30734697, PMCID: PMC6367626, DOI: 10.4269/ajtmh.18-0727.Peer-Reviewed Original ResearchConceptsMass drug administrationSoil-transmitted helminthsKintampo North MunicipalitySchool-aged childrenSingle nucleotide polymorphismsPolymerase chain reactionEffectiveness of MDAWild-type SNPsInfected study subjectsPeriodic mass drug administrationResistance-associated single nucleotide polymorphismsCross-sectional studyResistance-associated mutationsWorld Health OrganizationHookworm infectionDrug exposureHookworm eggsUnreported associationStudy subjectsDrug AdministrationPosttreatment samplesChemotherapeutic approachesGrowth delayHuman hookwormHealth Organization
2017
Does household access to improved water and sanitation in infancy and childhood predict better vocabulary test performance in Ethiopian, Indian, Peruvian and Vietnamese cohort studies?
Dearden KA, Brennan AT, Behrman JR, Schott W, Crookston BT, Humphries DL, Penny ME, Fernald LC. Does household access to improved water and sanitation in infancy and childhood predict better vocabulary test performance in Ethiopian, Indian, Peruvian and Vietnamese cohort studies? BMJ Open 2017, 7: e013201. PMID: 28270388, PMCID: PMC5353302, DOI: 10.1136/bmjopen-2016-013201.Peer-Reviewed Original ResearchChildren with access to improved sanitation but not improved water are at lower risk of stunting compared to children without access: a cohort study in Ethiopia, India, Peru, and Vietnam
Dearden KA, Schott W, Crookston BT, Humphries DL, Penny ME, Behrman JR, The Young Lives Determinants and Consequences of Child Growth Project Team. Children with access to improved sanitation but not improved water are at lower risk of stunting compared to children without access: a cohort study in Ethiopia, India, Peru, and Vietnam. BMC Public Health 2017, 17: 110. PMID: 28114914, PMCID: PMC5259877, DOI: 10.1186/s12889-017-4033-1.Peer-Reviewed Original Research
2016
Effectiveness of Albendazole for Hookworm Varies Widely by Community and Correlates with Nutritional Factors: A Cross-Sectional Study of School-Age Children in Ghana.
Humphries D, Nguyen S, Kumar S, Quagraine JE, Otchere J, Harrison LM, Wilson M, Cappello M. Effectiveness of Albendazole for Hookworm Varies Widely by Community and Correlates with Nutritional Factors: A Cross-Sectional Study of School-Age Children in Ghana. American Journal Of Tropical Medicine And Hygiene 2016, 96: 347-354. PMID: 27895280, PMCID: PMC5303035, DOI: 10.4269/ajtmh.16-0682.Peer-Reviewed Original ResearchConceptsEgg reduction rateCross-sectional studyMass drug administrationSchool-aged childrenEffectiveness of albendazoleCure rateDrug AdministrationMid-upper arm circumferenceSoil-transmitted helminth infectionsHost factorsNutritional factorsSingle-dose albendazoleOverall cure rateBlood hemoglobin levelsKintampo North MunicipalitySignificant community-level variationIndividual host factorsWorld Health OrganizationCommon STHHemoglobin levelsArm circumferenceHookworm infectionHelminth infectionsDeworming programsHookworm prevalence
2015
Using Positive Deviance to Understand the Uptake of Optimal Infant and Young Child Feeding Practices by Mothers in an Urban Slum of Mumbai
D’Alimonte M, Deshmukh D, Jayaraman A, Chanani S, Humphries DL. Using Positive Deviance to Understand the Uptake of Optimal Infant and Young Child Feeding Practices by Mothers in an Urban Slum of Mumbai. Maternal And Child Health Journal 2015, 20: 1133-1142. PMID: 26694045, DOI: 10.1007/s10995-015-1899-3.Peer-Reviewed Original ResearchConceptsYoung child feeding practicesChild feeding practicesHealth workersSocial groupsSemi-structured key informant interviewsOptimal infantFeeding practicesYoung child feeding behaviorsKey informant interviewsUrban slumsAcute malnutrition programsSocial supportAge z-scoreChild feeding behaviorsDisadvantaged contextsQualitative researchInformant interviewsDeviance researchCMAM programCommunity managementQualitative methodsDietary recallsMaternal healthIndex childMalnutrition programsCross-Sectional and Longitudinal Associations between Household Food Security and Child Anthropometry at Ages 5 and 8 Years in Ethiopia, India, Peru, and Vietnam 1–3
Humphries DL, Dearden KA, Crookston BT, Fernald LC, Stein AD, Woldehanna T, Penny ME, Behrman JR. Cross-Sectional and Longitudinal Associations between Household Food Security and Child Anthropometry at Ages 5 and 8 Years in Ethiopia, India, Peru, and Vietnam 1–3. Journal Of Nutrition 2015, 145: 1924-1933. PMID: 26084361, PMCID: PMC4516765, DOI: 10.3945/jn.115.210229.Peer-Reviewed Original ResearchResilience, stress, and life quality in older adults living with HIV/AIDS
Fang X, Vincent W, Calabrese SK, Heckman TG, Sikkema KJ, Humphries DL, Hansen NB. Resilience, stress, and life quality in older adults living with HIV/AIDS. Aging & Mental Health 2015, 19: 1015-1021. PMID: 25633086, PMCID: PMC4520800, DOI: 10.1080/13607863.2014.1003287.Peer-Reviewed Original Research
2013
Hookworm Infection among School Age Children in Kintampo North Municipality, Ghana: Nutritional Risk Factors and Response to Albendazole Treatment
Humphries D, Simms BT, Davey D, Otchere J, Quagraine J, Terryah S, Newton S, Berg E, Harrison LM, Boakye D, Wilson M, Cappello M. Hookworm Infection among School Age Children in Kintampo North Municipality, Ghana: Nutritional Risk Factors and Response to Albendazole Treatment. American Journal Of Tropical Medicine And Hygiene 2013, 89: 540-548. PMID: 23836564, PMCID: PMC3771297, DOI: 10.4269/ajtmh.12-0605.Peer-Reviewed Original ResearchConceptsKintampo North MunicipalityHookworm infectionCure rateSchool-aged childrenModest cure ratesSingle-dose albendazoleNutritional risk factorsLevels of antibodiesYears of ageAge childrenMalaria parasitemiaAlbendazole treatmentRisk factorsChildren 6InfectionInfection statusHealth careSignificant predictorsAnimal foodsHookwormAlbendazoleFurther investigationAgeChildrenLow consumptionPortion size variably affects food intake of 6-year-old and 4-year-old children in Kunming, China
Smith L, Conroy K, Wen H, Rui L, Humphries D. Portion size variably affects food intake of 6-year-old and 4-year-old children in Kunming, China. Appetite 2013, 69: 31-38. PMID: 23702260, PMCID: PMC4319705, DOI: 10.1016/j.appet.2013.05.010.Peer-Reviewed Original Research
2011
Epidemiology of Hookworm Infection in Kintampo North Municipality, Ghana: Patterns of Malaria Coinfection, Anemia, and Albendazole Treatment Failure
Humphries D, Mosites E, Otchere J, Twum WA, Woo L, Jones-Sanpei H, Harrison LM, Bungiro RD, Benham-Pyle B, Bimi L, Edoh D, Bosompem K, Wilson M, Cappello M. Epidemiology of Hookworm Infection in Kintampo North Municipality, Ghana: Patterns of Malaria Coinfection, Anemia, and Albendazole Treatment Failure. American Journal Of Tropical Medicine And Hygiene 2011, 84: 792-800. PMID: 21540391, PMCID: PMC3083749, DOI: 10.4269/ajtmh.2011.11-0003.Peer-Reviewed Original ResearchConceptsPoor nutritional statusHookworm infectionRisk factorsNutritional statusOverall egg reduction rateSerum immunoglobulin G (IgG) reactivitiesCross-sectional pilot studyEgg reduction rateImmunoglobulin G reactivityKintampo North MunicipalityAlbendazole therapyKintampo NorthMalaria coinfectionTreatment failureOverall prevalenceHigh prevalenceRepeat examinationEgg excretionSecretory antigensInfectionPilot studyCoinfectionSignificant reductionTherapyHigh rate
2003
Food, alcohol and cigarette availability and consumption in Almaty, Kazakstan: results and appraisal of a rapid assessment
Yim A, Humphries D, Abuova G. Food, alcohol and cigarette availability and consumption in Almaty, Kazakstan: results and appraisal of a rapid assessment. Public Health Nutrition 2003, 6: 791-800. PMID: 14641950, DOI: 10.1079/phn2003503.Peer-Reviewed Original Research
2002
Emerging Patterns of Hookworm Infection: Influence of Aging on the Intensity of Necator Infection in Hainan Province, People's Republic of China
Bethony J, Chen J, Lin S, Xiao S, Zhan B, Li S, Xue H, Xing F, Humphries D, Yan W, Chen G, Foster V, Hawdon JM, Hotez PJ. Emerging Patterns of Hookworm Infection: Influence of Aging on the Intensity of Necator Infection in Hainan Province, People's Republic of China. Clinical Infectious Diseases 2002, 35: 1336-1344. PMID: 12439796, DOI: 10.1086/344268.Peer-Reviewed Original Research
1997
The use of human faeces for fertilizer is associated with increased intensity of hookworm infection in Vietnamese women
Humphries DL, Stephenson LS, Pearce EJ, The PH, Dan HT, Khanh LT. The use of human faeces for fertilizer is associated with increased intensity of hookworm infection in Vietnamese women. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 1997, 91: 518-520. PMID: 9463654, DOI: 10.1016/s0035-9203(97)90007-9.Peer-Reviewed Original Research