In vitro Screening of Compounds against Laboratory and Field Isolates of Human Hookworm Reveals Quantitative Differences in Anthelmintic Susceptibility
Treger RS, Otchere J, Keil MF, Quagraine JE, Rai G, Mott BT, Humphries DL, Wilson M, Cappello M, Vermeire JJ. In vitro Screening of Compounds against Laboratory and Field Isolates of Human Hookworm Reveals Quantitative Differences in Anthelmintic Susceptibility. American Journal Of Tropical Medicine And Hygiene 2013, 90: 71-74. PMID: 24297811, PMCID: PMC3886431, DOI: 10.4269/ajtmh.12-0547.Peer-Reviewed Original ResearchConceptsField isolatesA. ceylanicumHookwormScreening of compoundsAncylostoma ceylanicumHuman hookwormAnthelmintic compoundsLaboratory strainsHookworm speciesPercent inhibitionSchool childrenTwofold increaseSelect compoundsAnthelmintic activityNovel anthelmintic compoundsAnthelmintic susceptibilityBrong Ahafo RegionIsolatesAhafo Region